Results 91 to 100 of about 47,786 (197)

A Critical Analysis of the Impact of Etoposide as a Topoisomerase II Inhibitor in Cervical Cancer Treatment: A Review

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian   +3 more
wiley   +1 more source

A Novel Treatment for Outer Ear Keloids Using Rubber Band Ligation—From Rear to Ear

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
We present a novel treatment for outer ear keloids using rubber band ligation in 3 patients. ABSTRACT This study demonstrates the use of a rubber band ligation for treating outer ear keloids. The method is effective, safe, and well‐tolerated by the patients.
Johanna Sundén   +2 more
wiley   +1 more source

Thrombotic Thrombocytopenic Purpura in a Patient With Triple‐Negative Breast Cancer Treated With PD‐L1 Inhibition and Taxane Chemotherapy

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
PET imaging of a 56 year old woman with HIV and advanced triple negative breast cancer with regional lymph node and bone metastases. ABSTRACT Thrombocytopenic purpura (TTP) is a hematologic emergency that may occur with PD‐L1 immunotherapy. New or worsening anemia and thrombocytopenia in patients started on PD‐L1 inhibitors should raise suspicion for ...
Jason Ke   +7 more
wiley   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

open access: yesJournal of Applied Toxicology, Volume 46, Issue 3, Page 950-960, March 2026.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston   +2 more
wiley   +1 more source

THE EFFECT OF SINGLE DOSE IMMEDIATE MITOMYCINE-C INSTILLATION OVER RECURRENCE IN LOW RISK SUPERFICIAL BLADDER TUMORS: SHORT TERM FOLLOW UP

open access: yesUrology Research and Practice, 2019
The effectiveness of a single dose mitomycin-C instillation immediately after TUR on short-term recurrences in patients with low-risk superficial bladder tumors has been investigated in this study.
G. Özer   +4 more
doaj  

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

open access: yesJournal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto   +6 more
wiley   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang   +4 more
wiley   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi   +13 more
wiley   +1 more source

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

open access: yesActa Ophthalmologica, Volume 104, Issue 2, Page e183-e190, March 2026.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy