Results 111 to 120 of about 90,988 (285)
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu +4 more
wiley +1 more source
Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis
The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe +7 more
wiley +1 more source
A randomized placebo controlled trial of Mitomycin - C in surgical outcome of primary endoscopic dacryocystorhinostomy [PDF]
Objective: To compare the patency of the stoma and relief of epiphora after endoscopic dacrocystorjinostomy (EnDCR) surgery with Mitomycin C and Placebo in cases of chronic dacrocystitis secondary to primary post saccal stenosis.
A.S. Harugop +6 more
doaj
Corneal Melt with Perforation Following Topical Mitomycin-C Application in Pterygium Excision
We report a case of corneal melt with perforation due to Mitomycin-C application during Pterygium excision. A 50-year-old male presented with sudden gross diminution of vision and pain in the left eye since one day.
Shashidhar Banigallapati, Akhil Bevara
doaj +1 more source
Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core
From bacterial predators to partners: phages in agriculture
Summary Bacteriophages, viruses that infect bacteria, are critical players for shaping the taxonomic and functional composition of plant‐associated microbiomes. Yet, their roles in plant health remain overlooked, along with their implications for sustainable agriculture.
Zahra Salehimoghaddam +2 more
wiley +1 more source
Majid Moshirfar,1– 3 William B West Jr,4 Dallin C Milner,5 Shannon E McCabe,1 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, 84020, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual
Moshirfar M +5 more
doaj
Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer [PDF]
In a personalized treatment designed for a patient with pancreatic cancer resistant to other treatments, the success of Mitomycin C (MMC) has been highlighted.
Armitage, Emily G. +8 more
core +1 more source
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee +5 more
wiley +1 more source

