Results 121 to 130 of about 14,552,787 (242)
Structure-activity relationships for mitomycin C and mitomycin A analogues
A set of 30 mitomycin C and mitomycin A analogues, including 5 new compounds, was screened against 3 different solid human tumor cell lines using the MTT tetrazolium dye assay.
Kunz, Kenneth Robert
core
Safety and Efficacy of Topical Mitomycin C in Myringotomy Patency
OBJECTIVE: To develop an alternative method for prolonged middle ear ventilation using topical mitomycin C. STUDY DESIGN AND SETTING: Twenty guinea pigs with normal ears had bilateral myringotomies performed using the argon laser.
Orlando Gomez‐Marin +5 more
core +1 more source
Long‐term outcomes following a 5‐year recurrence‐free interval in non‐muscle‐invasive bladder cancer
Objective To describe the recurrence and progression trends of non‐muscle‐invasive bladder cancer (NMIBC) during a 14‐year period in Denmark between 2009 and 2022. Furthermore, to evaluate the risk of late recurrence with or without progression in patients who initially experience a 5‐year recurrence‐free interval (RFI).
Peter B. Hjort +2 more
wiley +1 more source
We evaluated the histopathologic findings in seven patients who underwent surgical revision of the filtration site after trabeculectomy with mitomycin C because of persistent hypotonous maculopathy. Light microscopic examination of subconjunctival tissue
Geijssen, H. C. +6 more
core +1 more source
Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley +1 more source
The effectiveness of a single dose mitomycin-C instillation immediately after TUR on short-term recurrences in patients with low-risk superficial bladder tumors has been investigated in this study.
G. Özer +4 more
doaj +2 more sources
Study on the role of mitomycin C in the Management of ocular surface squamous neoplasia [PDF]
AIM OF THE STUDY: 1. To evaluate the role of Mitomycin C as an adjuvant therapy intraoperatively and post operatively in the management of Ocular Surface Squamous Neoplasia. 2.
Menaka, C
core
ADI‐PEG20 enhances melphalan‐induced DNA DSBs in UM cells. We describe potentiation of DNA DSBs in UM cell lines upon treatment with ADI‐PEG20 and melphalan (92.1 cells with STRIDE by intoDNA). ADI‐PEG20 suppresses multiple members of the FA pathway—a known resistance mechanism for melphalan—providing a rationale for exploring this drug combination in ...
Iuliia Pavlyk +10 more
wiley +1 more source
Susan J Lee1, Augusto Paranhos2, M Bruce Shields11Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, USA; 2Federal University of São Paulo, São Paulo, BrazilPurpose: To ...
Augusto Paranhos +2 more
core
S100A4 Orchestrates Fibroblast Fate to Drive Fibrotic Remodeling
Fibrotic stimuli induce S100A4 expression, promoting the activation of apoptosis‐resistant fibroblasts through engagement of ERK‐associated signaling. In fibroblasts, S100A4 orchestrates fibroblast fate by enhancing migration, promoting stress fiber formation, increasing ECM contractility, upregulating α‐SMA expression, and supporting survival ...
Spring Li +6 more
wiley +1 more source

