Results 161 to 170 of about 18,846,273 (226)

Use of Mitomycin C in Ophthalmic Surgery. [PDF]

open access: yesJ Curr Ophthalmol
Nassiri N   +5 more
europepmc   +1 more source

EpiLASIK with Mitomycin C

open access: yesEuropean Journal of Ophthalmology, 2010
Purpose Mitomycin C after photorefractive keratectomy (PRK) is used to reduce the development of haze and regression in higher intended corrections. The aim of this study was to investigate the safety, stability, and efficacy of EpiLASIK with mitomycin C.
Christoph, Winkler von Mohrenfels   +3 more
core   +4 more sources

Apoptosis in Keratocytes Caused by Mitomycin C [PDF]

open access: yesInvestigative Ophthalmology and Visual Science, 2003
PURPOSE: The purpose of this study was to quantify the effect of mitomycin C on rabbit keratocytes, with a view to determining its potential in modulating corneal stromal wound healing.
Tae-Im Kim   +2 more
exaly   +2 more sources
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Mitomycin C: a review

Cancer Treatment Reviews, 1976
Summary Preclinical 1. Mitomycin C is an alkylating agent requiring reduction of the quinone to be active. 2. The aziridine ring is essential for the antitumor activity of mitomycin C. 3. The degree of DNA cross-linking and tumor inhibition is proportional to the guanine and cytosine content of the DNA. 4.
S T, Crooke, W T, Bradner
openaire   +2 more sources

Mitomycin C.

Cancer chemotherapy and biological response modifiers, 1990
The mitomycins are antitumor antibiotics that are under investigation now for more than 30 years. Mitomycin C (MMC) is the best investigated subtype. It serves as a prototype for drugs with bioreductive alkylation, which is a unique feature of this class. MMC is mainly active under anaerobic circumstances.
J, Den Hartigh, J, Verweij, H M, Pinedo
  +9 more sources

Impact of Mitomycin-C Application Time on the Scleral Mitomycin-C Concentration

Journal of Ocular Pharmacology and Therapeutics, 2001
The aim of this study was to determine the effect of varying the application time of Mitomycin-C (MMC) on the scleral concentration of MMC. The sclerae of 14 human donor eyes were used for this study. The episcleral sides of the 4 scleral quadrants of each donor eye were exposed for 0.5, 1, 3 and 5 min to round, 8 mm-diameter sponges soaked with 50 ...
C, Vass   +4 more
openaire   +2 more sources

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