Intraperitoneal Perfusion with Cisplatin or Mitomycin C Improves Survival in Mice Bearing Peritoneal Metastases from Ovarian Cancer. [PDF]
Andersson Y +5 more
europepmc +1 more source
Mitomycin-C for HPV-Positive and HPV-Negative Platinum-Refractory, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Phase 2 Trial. [PDF]
Oppelt P +6 more
europepmc +1 more source
Three-year outcomes of two-stage intra-Tenon low-dose mitomycin C injection versus sponge application in trabeculectomy. [PDF]
Shih EJ, Chen YY.
europepmc +1 more source
Inhibiting Postoperative Fibrosis in Glaucoma Filtration Surgery Through Porous PLLA/RGD Membrane Mediated Local/Sustained Delivery of Mitomycin C. [PDF]
Wu X +7 more
europepmc +1 more source
Use of Mitomycin C in Ophthalmic Surgery. [PDF]
Nassiri N +5 more
europepmc +1 more source
Purpose Mitomycin C after photorefractive keratectomy (PRK) is used to reduce the development of haze and regression in higher intended corrections. The aim of this study was to investigate the safety, stability, and efficacy of EpiLASIK with mitomycin C.
Christoph, Winkler von Mohrenfels +3 more
core +4 more sources
Apoptosis in Keratocytes Caused by Mitomycin C [PDF]
PURPOSE: The purpose of this study was to quantify the effect of mitomycin C on rabbit keratocytes, with a view to determining its potential in modulating corneal stromal wound healing.
Tae-Im Kim +2 more
exaly +2 more sources
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Summary Preclinical 1. Mitomycin C is an alkylating agent requiring reduction of the quinone to be active. 2. The aziridine ring is essential for the antitumor activity of mitomycin C. 3. The degree of DNA cross-linking and tumor inhibition is proportional to the guanine and cytosine content of the DNA. 4.
S T, Crooke, W T, Bradner
openaire +2 more sources
The mitomycins are antitumor antibiotics that are under investigation now for more than 30 years. Mitomycin C (MMC) is the best investigated subtype. It serves as a prototype for drugs with bioreductive alkylation, which is a unique feature of this class. MMC is mainly active under anaerobic circumstances.
J, Den Hartigh, J, Verweij, H M, Pinedo
+9 more sources
Impact of Mitomycin-C Application Time on the Scleral Mitomycin-C Concentration
Journal of Ocular Pharmacology and Therapeutics, 2001The aim of this study was to determine the effect of varying the application time of Mitomycin-C (MMC) on the scleral concentration of MMC. The sclerae of 14 human donor eyes were used for this study. The episcleral sides of the 4 scleral quadrants of each donor eye were exposed for 0.5, 1, 3 and 5 min to round, 8 mm-diameter sponges soaked with 50 ...
C, Vass +4 more
openaire +2 more sources

