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Mitomycin C (z.B. Mitomycin C „Kyowa“)

2006
aufgrund zahlreicher Berichte uber Nekrosen wird Mitomycin C als gewebsnekrotisierend ...
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Bacteriocidal action of mitomycin C

Biochimica et Biophysica Acta, 1960
Abstract The bacteriocidal action of Mitomycin C has been investigated with respect to its biochemical, genetic and morphological correlates. All findings are consistent with the observation that cells treated with Mitomycin lose DNA, but not RNA or protein, to the surrounding medium.
E, REICH, A J, SHATKIN, E L, TATUM
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Mitomycin C extravasation injuries

Cancer, 1983
Mitomycin C extravasation produces a chronic painful ulceration similar to that of adriamycin. Pain marks the extravasation of this chemotherapeutic agent when it occurs. A complaint of pain during mitomycin administration should prompt immediate cessation of infusion and regular frequent follow-up.
L C, Argenta, E K, Manders
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Mitomycin-C in Congenital Glaucoma

Ophthalmic Surgery, Lasers and Imaging Retina, 1997
* BACKGROUND AND OBJECTIVE: To evaluate the adjunctive use of mitomycin-C (MMC) during trabeculotomy and trabeculectomy for eyes with highrisk congenital glaucoma. * PATIENTS AND METHODS: A prospective, randomized, double-blind study was performed to compare the effect of a single, 4-minute intraoperative exposure to 0.2 mg/ml (group 1) or 0 ...
H C, Agarwal   +4 more
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Potential Toxicity of Mitomycin C

Archives of Ophthalmology, 1991
To the Editor. —Chen et al1and Palmer2recently reported on the use of mitomycin C as adjunct chemotherapy during glaucoma filtration surgery. Both investigations followed similar protocols in which the episclera was soaked with a solution of 0.2 to 0.4 mg/mL of mitomycin C for 5 minutes before creating a sclerostomy.
R J, Derick   +3 more
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Mitomycin C extravasation ulcers

Journal of Surgical Oncology, 1985
AbstractIn a four‐year period, eight patients with mitomycin C extravasation ulcers were encountered. Mitomycin C extravasation produces a painful indolent ulcer that does not have any tendency to heal. If extravasation of the drug is recognized, infusion should be stopped immediately, and the site of infusion should be changed.
A K, Khanna   +3 more
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Dacryocystorhinostomy with Intraoperative Mitomycin C

Ophthalmology, 1997
To observe the effect of intraoperative mitomycin C on the size of the osteotomy site after dacryocystorhinostomy.:A total of 15 eyes of 14 patients diagnosed with primary acquired nasolacrimal duct obstruction were assigned randomly to either a mitomycin C group or a control group.
S C, Kao   +4 more
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Reductive activation of mitomycin C

Biochemistry, 1988
Mitomycin C, an antitumor antibiotic, is known to require reductive activation in order to function as an alkylating agent. In this work reduction has been carried out by using radiolytically produced formate radicals that reduce mitomycin C to its semiquinone in a clean rapid one-electron reaction.
B M, Hoey, J, Butler, A J, Swallow
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Mitomycin C in Photorefractive Keratectomy

Journal of Refractive Surgery, 2009
Purpose: To evaluate the outcome of primary or retreatment photorefractive keratectomy (PRK) or photo-therapeutic keratectomy (PTK) with mitomycin C (MMC) 0.02% applied prophylactically intraoperatively for the prevention of haze and regression in cases of significant haze and regression after primary PRK, due to previous ...
Ashraf, Shalaby   +2 more
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Renal toxicity of mitomycin-C

American Journal of Clinical Oncology, 1984
The clinical spectrum and the pathological findings of renal toxicity in four patients treated with mitomycin-C are described. Our experience and evidence in the literature indicates that the renal impairment appears to be total-dose-related, with most patients developing renal symptoms after receiving at least 60 mg of mitomycin-C.
T S, Ravikumar   +3 more
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