Results 161 to 170 of about 124,344 (344)

Comprehensive management of vulvovaginal cancers

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues   +5 more
wiley   +1 more source

Diminishing the side effect of mitomycin C by using pH-sensitive liposomes: in vitro characterization and in vivo pharmacokinetics

open access: yesDrug Design, Development and Therapy, 2018
Yi-Ping Fang,1,2 Pei-Yu Hu,1 Yaw-Bin Huang1,3 1School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 2Department of Medical Research, Kaohsiung Medical University Hospital, 3Center for Stem Cell Research, Kaohsiung Medical University ...
Fang YP, Hu PY, Huang YB
doaj  

Urothelial carcinoma: Perioperative considerations from top to bottom

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip   +8 more
wiley   +1 more source

The Protective Effect of Silibinin Against Mitomycin C–Induced Intrinsic Apoptosis in Human Melanoma A375-S2 Cells

open access: yesJournal of Pharmacological Sciences, 2009
Silibinin is known for its hepatoprotective, anti-inflammatory, and anti-carcinogenic effects. We found that silibinin exhibited a protective effect against chemotherapeutic reagent mitomycin C–induced cell death in A375-S2 cells in a p53-dependent ...
Yuan-yuan Jiang   +5 more
doaj  

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

open access: yesJournal of Applied Toxicology, Volume 45, Issue 8, Page 1455-1475, August 2025.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz   +12 more
wiley   +1 more source

Change in visual acuity and associated risk factors after trabeculectomy with adjunctive mitomycin C

open access: yesActa ophthalmologica, 2016
K. Kashiwagi   +6 more
semanticscholar   +1 more source

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

open access: yesJournal of Applied Toxicology, Volume 45, Issue 8, Page 1555-1571, August 2025.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal   +11 more
wiley   +1 more source

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