Research progress of antibody coupling technique in targeted drug delivery
Interdisciplinary Medicine, EarlyView.Abstract Antibody‐drug conjugates are a cutting‐edge biotechnology recently attracting wide attention in the medical field. Binding antibodies to drug molecules could deliver drugs precisely to the site of the lesion, which shows great potential in the treatment of tumors and immune diseases.
Meng Li +6 more
wiley +1 more source
Drug Design, Development and Therapy, 2018 Yi-Ping Fang,1,2 Pei-Yu Hu,1 Yaw-Bin Huang1,3 1School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 2Department of Medical Research, Kaohsiung Medical University Hospital, 3Center for Stem Cell Research, Kaohsiung Medical University ...
Fang YP, Hu PY, Huang YB
doaj
Continuous saline bladder irrigation for two hours following transurethral resection of bladder tumors in patients with non-muscle invasive bladder cancer does not prevent recurrence or progression compared with intravesical Mitomycin-C. [PDF]
, 2018 BackgroundIntravesical Mitomycin-C (MMC) following transurethral resection of bladder tumor (TURBT), while efficacious, is associated with side effects and poor utilization. Continuous saline bladder irrigation (CSBI) has been examined as an alternative.
Asanad, Kian +4 more
core +2 more sources
Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii
Journal of Applied Toxicology, EarlyView.ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz +12 more
wiley +1 more source
Evaluation of Corneal Endothelial Cells and Morphology in Mitomycin-C Augmented Trabeculectomy
Delhi Journal of Ophthalmology, 2020 Purpose: To evaluate the effect of Mitomycin-C (MMC) on corneal endothelial cells and morphology in Mitomycin-C augmented trabeculectomy Methods: In this study, 40 eyes of patients underwent trabeculectomy with Mitomycin-C (group 1) and 40 eyes of ...
Shalini Dhiman +2 more
doaj +1 more source
New P$c$N and AP$c$N functions over finite fields [PDF]
arXiv, 2020 Functions with low $c$-differential uniformity were proposed in $2020$ and attracted lots of attention, especially the P$c$N and AP$c$N functions, due to their applications in cryptography. The objective of this paper is to study P$c$N and AP$c$N functions.
arxiv
Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C [PDF]
, 2007 The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core
Simple one-pot fabrication of ultra-stable core-shell superparamagnetic nanoparticles for potential application in drug delivery [PDF]
, 2012 Ultrastable superparamagnetic core-shell nanoparticles of average diameter 80 nm have been fabricated via a simple one-pot method involving superparamagnetic iron oxide nanoparticles (SPIONs) core ([similar]50 nm in diameter) and lipid bilayer shell by ...
Al-Jamal +43 more
core +1 more source
Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal +11 more
wiley +1 more source
Journal of Pharmacological Sciences, 2009 Silibinin is known for its hepatoprotective, anti-inflammatory, and anti-carcinogenic effects. We found that silibinin exhibited a protective effect against chemotherapeutic reagent mitomycin C–induced cell death in A375-S2 cells in a p53-dependent ...
Yuan-yuan Jiang +5 more
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