Results 111 to 120 of about 94,931 (305)

The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization. [PDF]

, 2014
Fanconi anemia is a genetic disease resulting in bone marrow failure, birth defects, and cancer that is thought to encompass a defect in maintenance of genomic stability.
Alter, Andreassen, Andrew S. Marriott, Bogliolo, Bridge, Cantor, Cantor, Collins, Collins, Constantinou, Garaycoechea, Garcia-Higuera, Garcia-Higuera, Gary M. Kupfer, Gong, Green, Gupta, Howlett, Hussain, James B. Wilson, Kee, Kee, Kitao, Krejci, Kupfer, Levitus, Levran, Litman, London, Matsushita, Meetei, Moldovan, Montes de Oca, Nigel J. Jones, Park, Patricia McChesney, Patrick Sung, Peng, Reid, Seal, Simonne Longerich, Sobhian, Sommers, Stacy A. Williams, Thomashevski, Thompson, Vandenberg, Waisfisz, Wang, Wang, Wang, Wang, Wilson, Wu, Wu, Xia, Xiaoyong Chen, Xie, Yamashita, Youngho Kwon, Zhang   +60 more
core   +1 more source

Blindness and prognostic factors after trabeculectomy with mitomycin C in patients with open‐angle glaucoma with long‐term follow‐up

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the long‐term blindness rate and related prognostic factors in eyes with open‐angle glaucoma after trabeculectomy using adjunctive mitomycin C (MMC). Methods The retrospective cohort study included 714 eyes from 714 patients with open angle glaucoma who underwent trabeculectomy using MMC.
Masato Matsuo, Akira Sawada, Taishi Miyase, Masayuki Inuzuka, Masaomi Kubota, Tetsuya Yamamoto   +5 more
wiley   +1 more source

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Aydemir, Ü., Hartenstein, R., Munker, Reinhold, Pohlmann, H., Purmale, L., Reitmeier, M., Schorer, H.   +6 more
core   +1 more source

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed, Jesper Høiberg Erichsen, Afrouz Ahmadzadeh, Lars Morten Holm, Line Kessel, Daniella Bach‐Holm   +5 more
wiley   +1 more source

Tuberculosis vaccine strain _Mycobacterium bovis_ BCG Russia is a natural _recA_ mutant [PDF]

, 2008
The current tuberculosis vaccine is a live vaccine derived from _Mycobacterium bovis_ and attenuated by serial _in vitro_ passaging. All vaccine substrains in use stem from one source, strain Bacille Calmette-Guérin.
Erik C. Boettger, Peter M. Keller, Peter Sander   +2 more
core   +1 more source

Risk of metachronous upper tract urothelial carcinoma following non‐muscle‐invasive bladder cancer

BJU International, EarlyView.
Objective To determine the risk and timing of metachronous upper tract urothelial carcinoma (UTUC) after non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods In this multi‐institutional retrospective cohort study involving academic and community hospitals, clinicopathological data were collected from patients with NMIBC treated between 2005
Keiran J.C. Pace, Jethro C.C. Kwong, Harkanwal Randhawa, Maximiliano Ringa, Zizo Al‐Daqqaq, Yashan Chelliahpillai, Soomin Lee, Kellie Kim, Samuel Haile, Amna Ali, Marian Wettstein, Amy Chan, Nathan Perlis, Jason Lee, Robert Hamilton, Neil Fleshner, Antonio Finelli, Munir Jamal, Frank Papanikolaou, Thomas Short, Andrew Feifer, Girish Kulkarni, Alexandre R. Zlotta   +22 more
wiley   +1 more source

Effect of Topical Mitomycin C as an Adjunct to Dilation Therapy in Esophageal Strictures

Pakistan Journal of Medicine and Dentistry
Background: The treatment of choice for most esophageal strictures is esophageal dilatation but it has a low success rate. This study was conducted to determine the effect of topical mitomycin C as an adjunct to dilatation therapy in esophageal ...
Zunaira Hameed, Muhammad Tariq Aziz, Muhammad Aslam Sheikh, Saima Jabeen Joiya   +3 more
doaj   +1 more source

A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]

, 2005
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Bernier J, Budach W, Colevas AD, Colleoni M, Conti F, De Placido S, Degardin M, Dische S, Dobrowsky W, Gasparini G, Gralla R, Grau C, Haffty BG, Harrison LB, Hehr T, Kies MS, Koch WM, Munker R, Pouillart P, Poulsen MG, Regine WF, Shin DM, Siu LL, Vici P, Vokes EE, Wendt TG   +25 more
core   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis

The FEBS Journal, EarlyView.
The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe, Johannes Woelk, Julia Benz, Sarah Spoeck, William J. Olson, Andreas Villunger, Natascha Hermann‐Kleiter, Verena Labi   +7 more
wiley   +1 more source