Results 161 to 170 of about 361,857 (303)
Here, we explore a differential sex‐related metabolic‐immune relationship in melanoma. Melanoma tumours in male patients exhibit a higher LDH‐A‐driven production of lactate compared to their female counterparts. In turn, lactate acts as an immunosuppressive molecule, promoting pro‐tumoural Treg cells and suppressing anti‐tumoural CD8+ T‐cell activity ...
Marta Iozzo+10 more
wiley +1 more source
Methods for direct determination of mitomycin C in aqueous solutions and in urine
Stripping voltammetry (SV) is used to quantitatively determine concentrations of the anti-neoplastic drug mitomycin C (MMC) alone and in mixtures with 5-fluorouracil and cisplatin, both of which are used in combined chemotherapy with MMC.
Palecek Emil+3 more
doaj
Vascular‐targeted photodynamic therapy (VTP) using the photosensitizer WST11 is a non‐surgical tumor ablation approach. Light activation of WST11 leads to excessive generation of reactive oxygen species, which causes tumor vascular arrest, followed by destruction of tumor blood vessels and tumor necrosis.
Jie Chen+8 more
wiley +1 more source
Mitomycin C-induced expression of trpA of Salmonella typhimurium inserted into the plasmid ColE1 [PDF]
Eric U. Selker+2 more
openalex +1 more source
Cytomorphological Effects of Mitomycin C on Urothelial Cells: Eosinophils May Be Clue to The Drug-Induced Changes [PDF]
Cytomorphological changes of mitomycin C on urothelial cells may be misinterpreted as a neoplastic process. A 60-year old male patient who was given an eight-week course of intravesical mitomycin C due to non-invasive low grade transitional cell ...
Gulcin Guler Simsek+2 more
doaj
Breaking the Complexity of Cancer Using Computational Transcriptomic Network Biology
ABSTRACT While the landscapes of cancer mutations have been mostly clarified, in this study, we focused on the connective aggregates between mutations and phenotypes, named here as “gene transcriptomic networks,” aiming to survey computational network biology processes that have achieved significant results in cancer biology.
Heewon Park, Satoru Miyano
wiley +1 more source
Intrahepatic arterial infusion of combination of mitomycin-C and 5-fluorouracil in treatment of primary and metastatic liver carcinoma [PDF]
N. C. Misra+3 more
openalex +1 more source
The Riboflavin-sensitized Photooxidation of Mitomycin C by Near Ultraviolet Light Irradiation [PDF]
The riboflavin-sensitized photodestruction of mitomycin C by the irradiation with near ultraviolet light was investigated. The irradiation with near ultraviolet light abruptly decomposed mitomycin C in the presence of riboflavin, but mitomycin C slowly ...
Ueda Kazuo
core +1 more source
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang+4 more
wiley +1 more source
Interstitial lung disease in a patient treated with 5-fluorouracil and mitomycin C. [PDF]
J W L Fielding+2 more
openalex +1 more source