Results 61 to 70 of about 22,306,541 (256)
Future Postharvest and Food, EarlyView.The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
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Genetics and Molecular Biology, 2002 The frequencies of mitomycin C and cyclophosphamide-induced kidney and gill erythrocyte micronuclei were compared in Tilapia rendalli and Oreochromis niloticus.
Dario Palhares, Cesar Koppe Grisolia
doaj +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
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BMC Cancer, 2010 Background Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery.
Sørensen Olaf +6 more
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Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21WAF1/CIP1 activation
International Journal of Oncology, 2016 Mitomycin C (MC), a commonly used anticancer drug, induces DNA damage via DNA alkylation. Decarbamoyl mitomycin C (DMC), another mitomycin lacking the carbamate at C10, generates similar lesions as MC. Interstrand cross-links (ICLs) are believed to be the lesions primarily responsible for the cytotoxicity of MC and DMC. The major ICL generated by MC (α-
Cheng, Shu-Yuan +4 more
openaire +3 more sources
Impact of organic pollutants on phenotype and gene expression in human breast cancer cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin +7 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo +8 more
wiley +1 more source
HeliyonTo develop the liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for measuring mitomycin C in rat plasma, samples were processed using solid-phase extraction, with the internal standard being carbamazepine. A reversed phased C18 column was
Kyung-Sun Moon +4 more
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The Egyptian Journal of Otolaryngology, 2018 Aims and Objectives Synechia formation in a postoperative nasal cavity is a major factor for suboptimal clinical outcome in functional endoscopic sinus surgery (FESS).
Natarajan Ramalingam +3 more
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Immunosuppression and Surgery‐Free Interval in Granulomatosis With Polyangiitis Airway Stenosis
The Laryngoscope, EarlyView.Subglottic and tracheal stenosis are severe manifestations of granulomatosis with polyangiitis (GPA) that often require both endoscopic intervention and systemic immunosuppression. Rituximab may help stabilize GPA‐related airway disease by prolonging the interval between endoscopic procedures and delaying relapse.
Sydney J. Torres +6 more
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