Results 81 to 90 of about 361,857 (303)

Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells

open access: yesAdvanced Science, EarlyView.
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun   +12 more
wiley   +1 more source

Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review explores the role of radiotherapy (RT) in the multidisciplinary treatment of pancreatic ductal adenocarcinoma (PDAC), focusing on its integration with surgical strategies to improve resectability, local control, and survival outcomes while addressing potential challenges and future research directions.
Satoshi Yasuda   +4 more
wiley   +1 more source

Several extremal problems on graphs involving the circumference, girth, and hyperbolicity constant [PDF]

open access: yesarXiv, 2020
To compute the hyperbolicity constant is an almost intractable problem, thus it is natural to try to bound it in terms of some parameters of the graph. Let $\mathcal{G}(g,c,n)$ be the set of graphs $G$ with girth $g(G)=g$, circumference $c(G)=c$, and $n$ vertices; and let $\mathcal{H}(g,c,m)$ be the set of graphs with girth $g$, circumference $c$, and $
arxiv  

On t-extensions of abelian groups [PDF]

open access: yes, 2014
Let G and C be two discrete abelian groups. It is known that Pext(C,G) is a subgroup of Ext(C,G). In this paper, we introduce the t-extensions of G by C. We will show that the set of all t-extensions of G by C is a subgroup of Ext(C,G) which contains Pext(C,G).
arxiv   +1 more source

Analogues of hyperlogarithm functions on affine complex curves [PDF]

open access: yesarXiv, 2022
For $C$ a smooth affine complex curve, there is a unique minimal subalgebra $A_C$ of the algebra $\mathcal O_{hol}(\tilde C)$ of holomorphic functions on its universal cover $\tilde C$, which is stable under all the operations $f\mapsto \int f\omega$, for $\omega$ in the space $\Omega(C)$ of regular differentials on $C$.
arxiv  

Pediatric Glaucoma: a literature's review and analysis of surgical results [PDF]

open access: yes, 2015
The purpose of this paper is to review the surgical options available for the management of pediatric glaucoma, to evaluate their advantages and disadvantages together with their long-term efficacy, all with the intent to give guidelines to physicians on
IACOVELLO, DANIELA   +4 more
core   +4 more sources

Cytotoxicity and Characteristics of Mitomycin C

open access: yesOphthalmic Research, 1996
In order to evaluate the cytotoxicity of mitomycin C (MMC), the effects of MMC on cell viability, cell cycle and cell surface structure were studied using Chang's cultured human conjunctival cells. A 4- or 2-min exposure to MMC at concentrations ranging from 0.002 to 0.04% decreased the cell viability. The cell number was remarkably reduced by exposure
Naohide Ikoma   +2 more
openaire   +3 more sources

Topical application of mitomycin-C in corrosive esophageal strictures

open access: yesJournal of Indian Association of Pediatric Surgeons, 2005
Introduction: Corrosive ingestion is the major cause of esophageal stricture in our country. Mitomycin-C, an anthracycline derived from Streptomyces caespitosus, has both antineoplastic and antiproliferative properties. Use of mitomycin-C have been well
Kumar Arun, Bhatnagar V
doaj  

The abc-conjecture is true for at least $N(c), 1 \leq N(c) <φ(c)/2$, partitions a, b of c [PDF]

open access: yesarXiv, 2003
We prove that for any positive integer c there are at least N(c), $1\leq N(c) < \phi(c)/2$ representations of c as a sum of two positive integers a, b, with no common divisor, such that the N(c) radicals R(abc) are all greater than kc, where k an absolute constant.
arxiv  

Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells [PDF]

open access: yes, 2016
Epidemiological data indicate that the daily consumption of extra‑virgin olive oil (EVOO), a common dietary habit of the Mediterranean area, lowers the incidence of certain types of cancer, in particular bladder neoplasm. The aim of the present study was
Coccia, Andrea   +5 more
core   +1 more source

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