Results 1 to 10 of about 13,073 (205)

Mitomycins syntheses: a recent update [PDF]

Beilstein Journal of Organic Chemistry, 2009
Mitomycins are a class of very potent antibacterial and anti-cancer compounds having a broad activity against a range of tumours. They have been used in clinics since the 1960’s, and the challenges represented by their total synthesis have challenged generations of chemists.
Jean-Christophe Andrez
openaire   +4 more sources

A systematic study on the chemical stability of mitomycin A and mitomycin B.

Chemical and Pharmaceutical Bulletin, 1986
The kinetics and mechanisms of the degradation of mitomycin A and mitomycin B in aqueous solution were investigated by means of ultraviolet (UV) spectrophotometry and high-performance liquid chromatography (HPLC). The influences of pH, buffers and temperature on the degradation were quantified.
Oeds A.G.J. van der Houwen, Hilde Rosing, Jos H. Beijnen, Willy J. M. Underberg   +3 more
openaire   +4 more sources

Mitomycin C in ophthalmology

Journal of the Scientific Society, 2012
Introduction to the use of Mitomycin C in ophthalmology was a significant development in the 1960s. Its use and application in ophthalmology has been increasing in recent years, because of its modulatory effects on wound healing. Current applications of this drug in ophthalmology include pterygium surgery, glaucoma surgery, corneal refractive surgery ...
R. S. Mudhol, Rekha Mudhol, N. D. Zingade   +2 more
openaire   +3 more sources

Studies on the Chemistry of Mitomycins

Synlett, 1990
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Masaji Kasai, Motomichi Kono
openaire   +4 more sources

Mitomycin C in pterygium treatment

International Journal of Ophthalmology, 2016
Pterygium is a benign lesion usually growing from the nasal side of the conjunctiva onto the cornea. Most cases of pterygium does not cause problem or requires specific treatment. The exact cause of pterygium is not clear yet, but some factors are pointed as causes, being the most important the long-term ultraviolet ray exposure.
Thiago Gonçalves dos Santos Martins, Ana Luiza Fontes de Azevedo Costa, Paulo Schor, Roger Chammas, Milton Ruiz Alves   +4 more
openaire   +4 more sources

Cytotoxicity, crosslinking and biological activity of three mitomycins. [PDF]

Bioorg Chem, 2022
Cheng SY, Delgado-Cruzata L, Clement CC, Zacarias O, Concheiro-Guisan M, Towler N, Snyder T, Zheng M, Almodovar N, Gonzalez C, Romaine M, Sapse AM, Champeil E.   +12 more
europepmc   +1 more source

The aminoshikimic acid pathway in bacteria as source of precursors for the synthesis of antibacterial and antiviral compounds. [PDF]

J Ind Microbiol Biotechnol, 2021
Escalante A, Mendoza-Flores R, Gosset G, Bolívar F.   +3 more
europepmc   +1 more source

Recent updates and future perspectives in aziridine synthesis and reactivity. [PDF]

Chem, 2023
Dequina HJ, Jones CL, Schomaker JM.
europepmc   +1 more source

Efficient synthesis of aziridinecyclooctanediol and 3-aminocyclooctanetriol. [PDF]

Beilstein J Org Chem, 2022
Salamci E, Lafzi AK.
europepmc   +1 more source

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin. [PDF]

Molecules, 2021
Leng D, Sheng Y, Wang H, Wei J, Ou Y, Deng Z, Bai L, Kang Q.   +7 more
europepmc   +1 more source