Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA. [PDF]
Aguilar W +7 more
europepmc +1 more source
Abstract Purpose To assess the prognosis and determinants of survival after orbital exenteration in patients with conjunctival melanoma (CoM). Methods In a retrospective study, 27 consecutive patients who underwent exenteration for CoM from 2001 to 2023 were included.
David Chetroiu +7 more
wiley +1 more source
Long‐term outcomes of a cascading salvage strategy for high‐risk non‐muscle‐invasive bladder cancer
Objective To report long‐term oncological outcomes of patients with high‐risk non‐muscle‐invasive bladder cancer (HR‐NMIBC) undergoing bladder‐sparing therapy (BST) after bacillus Calmette–Guérin (BCG) failure. Patients and Methods We retrospectively reviewed patients with HR‐NMIBC treated from 2000 to 2025 with intravesical therapies after BCG failure,
Ian M. McElree +5 more
wiley +1 more source
BWCFF, a severe disease with neurological symptoms, is caused by mutations in the cytoskeletal actin genes. Patient‐derived fibroblasts carrying the R196H β‐actin mutation were compared to wild type cells. The mutant cells displayed slower proliferation and migration and a lower F‐actin content, which correlated with reduced cell stiffness ...
Éva Gráczer +12 more
wiley +1 more source
Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery in colorectal carcinoma at high risk of peritoneal carcinomatosis: short-term and long-term outcomes from the CHECK study - protocol for a randomised, multicentre, phase 3 trial. [PDF]
Pacelli F +11 more
europepmc +1 more source
Mechanistic Studies of Aziridine Formation Catalyzed by Mononuclear Non-Heme Iron Enzymes. [PDF]
Cha L +6 more
europepmc +1 more source
Comparative Analysis of Transcriptomic Response of Escherichia coli K-12 MG1655 to Nine Representative Classes of Antibiotics. [PDF]
Bie L +6 more
europepmc +1 more source
Precursor-Directed Biosynthesis of Azinomycin A and Related Metabolites by Streptomyces sahachiroi [PDF]
Azinomycins A and B are bioactive compounds produced by Streptomyces species. These naturally occurring antibiotics exhibit potent in vitro cytotoxic activity, promising in vivo antitumor activity and exert their effect by disruption of DNA replication ...
Sebbar, Abdel-Ilah
core
Protective effects of steroidal alkaloids isolated from Solanum paniculatum L. against mitomycin cytotoxic and genotoxic actions [PDF]
Pabline Marinho Vieira +3 more
openalex +1 more source
Bulky Adducts in Clustered DNA Lesions: Causes of Resistance to the NER System. [PDF]
Naumenko NV, Petruseva IO, Lavrik OI.
europepmc +1 more source

