Results 61 to 70 of about 960 (156)
R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking
R17 is a viral protein that binds heparan sulfate glycosaminoglycans and traffics them to the lysosome, leading to their degradation in a manner that does not require the presence of the cation‐independent mannose‐6‐phosphatre receptor. In BxPC3 pancreatic cancer cells, this loss in heparan sulfate results in the reduction of cell migration.
Pranali Bedekar +7 more
wiley +1 more source
Accidental Extravasation of Mitomycin C into the Subcutaneous Tissue. [PDF]
Chung J +4 more
europepmc +1 more source
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley +1 more source
Mitomycins, produced by several Streptomyces strains, are potent anticancer antibiotics that comprise an aziridine ring fused to a tricyclic mitosane core. Mitomycins have remarkable ability to crosslink DNA with high efficiency.
Ogasawara, Yasushi +4 more
core
The addition of (methylene-2H2)-3-amino-5-hydroxybenzyl alcohol (8) hydrochloride to growing cultures of Streptomyces verticillatus inhibits production of the mitomycin antibiotic porfiromycin (2) by the microorganism.
V Rukachaisirikul, RW Rickards
core +1 more source
Efficient synthesis of aziridinecyclooctanediol and 3-aminocyclooctanetriol. [PDF]
Salamci E, Lafzi AK.
europepmc +1 more source
Long‐term outcomes following a 5‐year recurrence‐free interval in non‐muscle‐invasive bladder cancer
Objective To describe the recurrence and progression trends of non‐muscle‐invasive bladder cancer (NMIBC) during a 14‐year period in Denmark between 2009 and 2022. Furthermore, to evaluate the risk of late recurrence with or without progression in patients who initially experience a 5‐year recurrence‐free interval (RFI).
Peter B. Hjort +2 more
wiley +1 more source
Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley +1 more source
ADI‐PEG20 enhances melphalan‐induced DNA DSBs in UM cells. We describe potentiation of DNA DSBs in UM cell lines upon treatment with ADI‐PEG20 and melphalan (92.1 cells with STRIDE by intoDNA). ADI‐PEG20 suppresses multiple members of the FA pathway—a known resistance mechanism for melphalan—providing a rationale for exploring this drug combination in ...
Iuliia Pavlyk +10 more
wiley +1 more source
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn +4 more
wiley +1 more source

