Results 151 to 160 of about 59,394 (245)

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Greek Registry for Amyotrophic Lateral Sclerosis (ALS-GR): An Observational Cohort of Individuals With ALS Across 11 Specialized Centers in Greece. [PDF]

Eur J Neurol
Liampas I, Kimiskidis VK, Zouvelou V, Veltsista D, Moscholouri A, Triantafyllou E, Daponte A, Xirou S, Sterpi AE, Salakou S, Poulidou V, Arnaoutoglou M, Tsouris Z, Ralli S, Dardiotis E, Papagiannopoulos S, Zampetakis A, Zaganas Ι, Mitsias P, Giannakis A, Konitsiotis S, Kefalas F, Alexiou E, Stoiloudis P, Parissis D, Kiamelidis S, Terzoudi A, Tsivgoulis G, Rentzos M, Chroni E.   +29 more
europepmc   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts. [PDF]

Cell Metab
Tiash S, Patel SA, Russo M, Suresh A, Pang B, Pai YL, Jia W, Field RL, Pietka T, Abumrad NA, Smith GI, Samovski D, Klein S, Brestoff JR, Crewe C.   +14 more
europepmc   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Anesthetic and Transfusion Management of an Immunosuppressed Patient With Infective Endocarditis and Severe Platelet Allergy Undergoing Redo Aortic Root Surgery. [PDF]

Cureus
Sarridou D, Ioannidis R, Iatridi F, Mitos G, Amaniti E.   +4 more
europepmc   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Complete mitochondrial genome of <i>Pseudophlugiolopsis bitubera</i> (Orthoptera:Tettigoniidae:Meconematinae). [PDF]

Microbiol Resour Announc
Zhang Z, Yu T, Bian X, Zhang B.
europepmc   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

Bystander training to prevent gender-based violence against female university students: a scoping review. [PDF]

Rev Esc Enferm USP
Tassinari TT, Padoin LM, Molina LA, Paula CC, Padoin SMM.   +4 more
europepmc   +1 more source