Results 161 to 170 of about 59,394 (245)

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

Protocol for mitochondrial DNA isolation from Macrobrachium rosenbergii and Penaeus monodon using differential centrifugation. [PDF]

STAR Protoc
Pal DC, Karim MM.
europepmc   +1 more source

Responsive nanoheterojunctions for built‐in electric field‐promoted cascade tumor targeting and cuproptosis‐based therapy

Responsive Materials, EarlyView.
Nanoheterojunctions have been synthesized as responsive biomaterials for cascade targeting of tumor cells and mitochondria, ROS‐mediated apoptosis and Cu‐promoted cuproptosis. And drug‐device‐field integration as an advanced paradigm of tumor treatment was employed for photo‐triggered tumor cell elimination in vitro and lesion eradication in vivo ...
Zhe Liu, Yandai Lin, Xuehui Li, Fengqi Xuan   +3 more
wiley   +1 more source

Complete mitochondrial genome of <i>Guangxia longlina</i> (Orthoptera: Tettigoniidae: Meconematinae). [PDF]

Microbiol Resour Announc
Li Z, Yao Y, Bian X, Zhang B.
europepmc   +1 more source

AS1517499 Protects Auditory Hair Cells Against Cisplatin‐Induced Damage In Vitro

Sensory Neuroscience, EarlyView.
AS1517499 alleviates cisplatin‐induced ototoxicity by reducing oxidative stress and apoptosis in cochlear hair cells. AS1517499 pretreatment reduces cisplatin‐induced cellular damage in HEI‐OC1 cells and hair cell loss in cochlear explants, thereby improving cell viability and preserving cochlear hair cells.
Qin Gu, Yue Qiu, Zhijie Fang, Xiaohong Lv, Song Gao, Zhiqiang Lin   +5 more
wiley   +1 more source

Deeply supervised two stage generative adversarial network for stain normalization. [PDF]

Sci Rep
Du Z, Zhang P, Huang X, Hu Z, Yang G, Xi M, Liu D.   +6 more
europepmc   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

Smart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song, Hui Bian, Lei Liu, Gahyeon Park, Bingqing Sun, Qiongzheng Hu, Juyoung Yoon   +6 more
wiley   +1 more source

Characterization of the Complete Mitochondrial Genome of <i>Cricula andrei</i> (Lepidoptera: Saturniidae) and Comparison with Other Lepidoptera Species. [PDF]

Curr Issues Mol Biol
Meng X, Yang W, Liu Y, Zhang Y, Luo D, Wei S, Guo Y, Qian C.   +7 more
europepmc   +1 more source

A photoimmune synergizing RNA interference technology for highly effective antitumor treatment

Smart Molecules, EarlyView.
We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia, Bingbing Wu, Xueze Zhao, Wen Sun, Jianjun Du, Jiangli Fan, Xiaojun Peng   +6 more
wiley   +1 more source

The complete mitochondrial genome of <i>Glyptotendipes tokunagai</i> (Arthropoda; Insecta; Diptera; Chironomidae). [PDF]

Microbiol Resour Announc
Huang X, Huang D, Chen H, Zhu C, Wang W, Ouyang S, Wu X, Zhou C.   +7 more
europepmc   +1 more source