Results 171 to 180 of about 7,933 (262)

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, Volume 13, Issue 25, 4 May 2026.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Evaluation of the Winemaking Characteristics of High Anthocyanin Teinturier Grape Varieties (Lines). [PDF]

Foods
Zhang H, Zhang X, Deng Y, Zhai Y, Du Y, Fang Y, Zhang K, Chen K.   +7 more
europepmc   +1 more source

Rising Inpatient Demands for Inherited Metabolic Disorders: Impact on Pediatric Capacity

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1423-1426, June 2026.
Maria Paula Silva, Kirsten Havens, Katherine Arduini, Anne Kozek, Erika Vucko, Joel Charrow, Joshua Baker, Carlos E. Prada   +7 more
wiley   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Electron tomography reveals mitochondrial network and cristae remodelling during cell differentiation in the human placenta

Acharya S, Hanssen E, Botha VB, Smith TM, Jayatissa S, Jayatissa S, Trifunovic Z, Bartho LA, Schjenken JE, Kaitu’u-Lino TJ, Perkins AV, James JL, Pringle KG, Bouwer JC, Smith R, Fisher JJ.   +15 more
europepmc   +1 more source

Complete mitochondrial genome of <i>Qiongphasma jianfengense obtusicristata</i> (Phasmatodea: Lonchodidae: Necroscinae). [PDF]

Microbiol Resour Announc
Guo J, Luo T, Bian X.
europepmc   +1 more source

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer. [PDF]

Cell Death Dis
Bidgood CL, Philp LK, Rockstroh A, Lehman M, Nelson CC, Sadowski MC, Gunter JH.   +6 more
europepmc   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

A fully automated morphological analysis of yeast mitochondria from wide-field fluorescence images. [PDF]

Sci Rep
Vojtová J, Čapek M, Willeit S, Groušl T, Chvalová V, Kutejová E, Pevala V, Valášek LS, Rinnerthaler M.   +8 more
europepmc   +1 more source