Results 41 to 50 of about 7,933 (262)

Lenguaje metafórico en el mundo del fútbol

Apunts: Educación Física y Deportes, 2017
El propósito de este estudio es demostrar que el fútbol actual se ha convertido en un sustituto de la religión. No solo como un hecho trascendente sino como un hecho real. La dimensión planetaria que este ha adquirido en los últimos años, nos puede hacer
Javier Arranz Albó
doaj   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Some more spread myths about ICT in education. How to avoid them?

Revista MENDIVE, 2021
The irruption of electronic devices in all spheres of society, with screens of all sizes and with multiple features, is increasing, the rapid automation of most processes, including educational ones, has generated or re-emerged different myths, in the ...
Raidell Avello Martínez, Klinge Orlando Villalba-Condori, Dennis Arias-Chavez   +2 more
doaj  

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Mito & contracultura

Mediações - Revista de Ciências Sociais, 2007
Considerada irracional desde os seus primórdios, a crítica à contracultura revelou-se incapaz de perceber a revolução cognitiva que se instaurava com as diferentes práticas de espiritualidade. Substituindo a lógica racionalista da exclusão pela lógica da inclusão, onde os elementos se equivalem, o movimento contracultural resgatou a experiência mítica,
openaire   +4 more sources

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Espacio y tiempo sagrado en los Andes

Allpanchis, 1988
Todas las sociedades y culturas del mundo han establecido sus espacios y tiempos sagrados en contraposición de lo profano que significa lo natural, lo cotidiano de la vida del hombre.
Bernardino Zecenarro Villalobos
doaj   +1 more source

MYTHICIST : SEBUAH MITOS TENTANG "MITOS"

SOLA GRATIA: Jurnal Teologi Biblika dan Praktika, 2020
Abstrak: Meskipun secara umum eksistensi historis figur Yesus merupakan kebenaran yang dianggap aksiomatis,sejarah mencatat adanya beberapa orang dari abad-abad lampau, yang menyangsikan bahwa Pribadi ini benar-benar pernah ada. Hanya saja, ide ini tidak mendapat sambutan yang serius pada masa itu. Meski demikian, ini tidak menyurutkan beberapa pemikir
openaire   +2 more sources

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Representación social de la pobreza

INFAD
Actualmente, no pocas veces continúan vigentes patrones de comportamiento discriminatorio contra las personas que se encuentran en situación de pobreza, apoyados en mitos, falsas creencias, ideas estereotipadas, prejuicios y estigmas hacia las personas ...
Beatriz Lázara Gandarillas, Ana Isabel Isidro de Pedro   +1 more
doaj   +1 more source