Results 151 to 160 of about 229,134 (290)

Integrating artificial intelligence (AI) into colorectal cancer reporting

The Journal of Pathology, EarlyView.
Abstract Artificial intelligence (AI) and deep learning (DL) are transforming cancer research and clinical care, with histopathology playing a central role in this transformation. In colorectal cancer (CRC), the second leading cause of cancer mortality world‐wide, multimodal and vision‐language models (VLMs) hold particular promise for enhancing the ...
Konstantin Bräutigam, Ann‐Marie Baker, Viktor H Koelzer, Jakob N Kather, Trevor A Graham   +4 more
wiley   +1 more source

Condensin complexes: from chromatin organization to disease. [PDF]

Nucleus
Shu L, Zhang H.
europepmc   +1 more source

Turning rice meiosis into mitosis

Cell Research, 2016
D. Mieulet, S. Jolivet, M. Rivard, Laurence Cromer, A. Vernet, Pauline Mayonove, L. Pereira, G. Droc, B. Courtois, E. Guiderdoni, R. Mercier   +10 more
semanticscholar   +1 more source

Clinicopathological significance of loss of Y chromosome in male meningiomas

The Journal of Pathology, EarlyView.
Abstract Male meningiomas, comprising approximately 30% of all meningiomas, are more frequently high‐grade and associated with poorer clinical outcomes compared to their female counterparts. Although Y chromosome alterations have been studied in various male‐predominant tumors, a limited number of studies have evaluated their role in meningiomas.
Maki Sakaguchi, Masafumi Horie, Yukinobu Ito, Shingo Tanaka, Hiroko Ikeda, Mitsutoshi Nakada, Akihiko Yoshizawa, Daichi Maeda   +7 more
wiley   +1 more source

Conditional Localization Pharmacology Manipulates the Cell Cycle with Spatiotemporal Precision. [PDF]

J Am Chem Soc
Deng C, Lan YC, Chen GY, Ekeabu CS, Doan Q, Chung M, Lampson MA, Chenoweth DM.   +7 more
europepmc   +1 more source

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

PROTEOMICS, EarlyView.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives, James M. Fulcher, Alex R. Bautista, Reta Birhanu Kitata, Sarah M. Williams, David A. Bennett, Philip L. De Jager, Vladislav A. Petyuk   +7 more
wiley   +1 more source

Quadra Sense: A Fusion of Deep Learning Classifiers for Mitosis Detection in Breast Cancer Histopathology. [PDF]

Diagnostics (Basel)
Alhassan AM, Altmami NI.
europepmc   +1 more source

Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain.

Neuron, 2016
L. Pilaz, J. McMahon, Emily E Miller, Ashley L. Lennox, Aussie Suzuki, E. Salmon, Debra L. Silver   +6 more
semanticscholar   +1 more source

Computational Characterization of the Role of LEM2/LaminA Interactions on the Stability of BAF‐Dimer Using Molecular Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil, Alexander von Appen, Thomas D. Kühne   +2 more
wiley   +1 more source

GMCL1 controls 53BP1 stability and modulates taxane sensitivity. [PDF]

Elife
Kito Y, González-Robles TJ, Kaisari S, Pae J, Garcia SF, Ortiz-Pacheco J, Ueberheide B, Marzio A, Róna G, Pagano M.   +9 more
europepmc   +1 more source