Results 131 to 140 of about 181,332 (213)

Direct Implantation of Transcatheter Valve in Mitral Annular Calcification: A Multi-Center Study.

Annals of Thoracic Surgery
BACKGROUND Mitral valve replacement (MVR) in the setting of severe annular calcification (MAC) is associated with high morbidity and mortality. Direct surgical implantation of a transcatheter heart valve (THV) through a trans-atrial approach is a ...
A. F. Hassanabad, M. Rabbani, Derrick Y. Tam, G. Bisleri, David Latter, R. Guo, Michael W. A. Chu, W. Kent, C. Adams   +8 more
semanticscholar   +1 more source

Duration‐Dependent Cardiac Effects of Anabolic‐Androgenic Steroid Use in Strength‐Trained Athletes: A Systematic Review and Meta‐Analysis

Echocardiography, Volume 43, Issue 9, September 2026.
Anabolic‐androgenic steroid use is associated with cardiac structural remodeling and functional impairment in strength‐trained athletes. Longer exposure was significantly associated with greater reductions in LVEF and increases in LVMI and posterior wall thickness, while other echocardiographic abnormalities showed heterogeneous temporal patterns ...
Matheus de Medeiros Fernandes, Pedro Gomes Batista, Camila Viviane Ribera Chagas, Railla Raquel Albino dos Santos Silva, Fernanda Medeiros Santos, Miguel Chaves Lenzi, Felipe de Medeiros Fernandes, Ranna Santos Pessoa, Patrícia Jovelina de Freitas, Flávio Henrique Amaral Pires Véras, Stephan Barisic Junior, Douglas Nunes Cavalcante, Juliana Giorgi, Caroline Fischer‐Bacca   +13 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, Volume 293, Issue 18, Page 5600-5626, September 2026.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Outcomes after transcatheter mitral valve implantation in valve‐in‐valve, valve‐in‐ring, and valve‐in‐mitral annular calcification

Catheterization and cardiovascular interventions
We aimed to evaluate transcatheter mitral valve implantation (TMVI) using predominantly balloon‐expandable transcatheter heart valves (THV) in patients with a landing zone for a percutaneously delivered prosthesis.
H. Alvarez-Covarrubias, M. Joner, Marius Lutz, E. Xhepa, N. Mayr, M. Lachmann, S. Cassese, Tobias Rheude, Costanza Pellegrini, S. Kufner, H. Schunkert, A. Kastrati, M. Erlebach, R. Lange, H. Ruge   +14 more
semanticscholar   +1 more source

Efficacy and Safety of a Single‐Pill Triple Combination of Valsartan, Amlodipine, and Chlorthalidone in Patients With Essential Hypertension Inadequately Controlled on Dual Therapy With Valsartan and Amlodipine: A Randomized, Double‐Blind, Multicenter, Phase 3 Trial

The Journal of Clinical Hypertension, Volume 28, Issue 9, September 2026.
ABSTRACT Many hypertensive patients require three or more antihypertensive agents to achieve target blood pressure. This randomized, double‐blind, multicenter phase 3 trial conducted in South Korea evaluated the efficacy and safety of a single‐pill triple combination therapy with valsartan (Val), amlodipine (Aml), and chlorthalidone (CTD) in patients ...
In‐Jeong Cho, Soon Jun Hong, Min Gyu Kong, Sang‐Ho Jo, Eun Joo Cho, Cheol Ung Choi, Jung Hyun Choi, Dae‐Hee Kim, Ju Han Kim, Sang‐Hyun Ihm, Wook Bum Pyun   +10 more
wiley   +1 more source

Multidomain Arterial Afterload and Left Atrial–Left Ventricular Coupling in Hypertensive Phenotypes

The Journal of Clinical Hypertension, Volume 28, Issue 9, September 2026.
ABSTRACT Brachial blood pressure may not fully reflect the multidimensional arterial load associated with left atrial–left ventricular (LA–LV) coupling. In this cross‐sectional study, we examined local carotid pulse wave velocity (PWV), cuff‐derived arterial pressure–volume index (API), and arterial velocity–pulse index (AVI), separately and as a ...
Yiran Luo, Lina Zhao, Sha Li, Yueyao Zhao, Fangfang Lu, Bei Zhang   +5 more
wiley   +1 more source

Prospective echocardiographic characterization of postnatal cardiac development in C57BL/6 mice: Strain analysis between birth and adulthood

Physiological Reports, Volume 14, Issue 18, September 2026.
Abstract Echocardiography is critical for characterizing murine models of cardiovascular disease, yet normative data for the early postnatal period, particularly advanced functional metrics like myocardial strain, remain undefined. This developmental window features rapid cardiac maturation and is central to modeling congenital and neonatal heart ...
Sehjin Jo, George Spyropoulos, Logan G. Hart, Taylor A. Covington, Arvind K. Pandey, Thomas Michel, Fotios Spyropoulos   +6 more
wiley   +1 more source

Impact of mitral valve intervention and frailty on outcomes of severe mitral regurgitation due to severe mitral annular calcification.

Progress in cardiovascular diseases
BACKGROUND Mitral annular calcification (MAC) can be complicated by mitral regurgitation (MR). However, data on outcomes of severe MR caused by MAC are limited.
Mohammad Al Zein, Y. Okushi, Shinya Unai, Gosta B. Pettersson, A. Gillinov, Per Wierup, Richard A. Grimm, Brian P. Griffin, Bo Xu   +8 more
semanticscholar   +1 more source

Kaplan Meier survival curve for subjects based on presence (+) or absence (-) of Coronary Artery Calcium, Mitral Annular Calcification.

, 2015
Abbreviations: Coronary Artery Calcification (CAC), Mitral Annular Calcification (MAC).
David Glidden (375115), Karen Ordovas (763570), Steven G. Deeks (131630), Jeffrey N. Martin (131623), Priscilla Y. Hsue (528198), Ann F. Bolger (763571), David C. Lange (763568), Eric A. Secemsky (763569)   +7 more
core   +1 more source

Mitral Annular Calcification-Related Mitral Stenosis: 5-Year Outcomes and Prognostic Determinants in the JAMAC Study.

Journal of the American College of Cardiology
BACKGROUND Mitral annular calcification (MAC)-related mitral stenosis is associated with increased mortality, but robust long-term outcomes remain unclear.
Nahoko Kato, Takatomo Watanabe, Takuma Ishihara, N. Kagiyama, Maika Shimizu, Yukio Abe, Y. Matsumura, T. Onishi, Yasushi Ichikawa, Koki Nakanishi, Yasuki Nakada, Nozomi Fukuda, C. Izumi, S. Kurashima, Yoshihiro Seo, S. Kikuchi, Nozomi Watanabe, K. Nagatomo, Y. Izumi, Ayumi Nakabo, Masao Daimon, Hiroyuki Watanabe, H. Okura   +22 more
semanticscholar   +1 more source