Results 201 to 210 of about 5,407,498 (292)

Risk Factors for Myocardial Injury During Cardio‐Pulmonary Bypass‐Assisted Heart Surgery: A Retrospective Single‐Center Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 10, November 2026.
ABSTRACT Introduction Myocardial injury is a significant contributor to 30‐day mortality after cardiac surgery with cardiopulmonary bypass. We aimed to investigate the association between mean arterial pressure, norepinephrine use during the aorta cross‐clamp period, and aorta cross‐clamp duration with myocardial injury during cardiopulmonary bypass ...
Julie T. Holm   +6 more
wiley   +1 more source

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1605-1615, November 2026.
Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah   +17 more
wiley   +1 more source

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1657-1667, November 2026.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto   +11 more
wiley   +1 more source

Evaluating Harm Reduction Advice From Large Language Models

open access: yesDrug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Large language models (LLM) and generative Artificial Intelligence are increasingly providing health information. We have applied a novel method to evaluate the harm reduction information generated by popular LLMs. We focused on the filtration of oral medications for injection and the availability of local harm reduction services.
Khy Choo   +3 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, Volume 293, Issue 21, Page 6444-6466, November 2026.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

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