Results 41 to 50 of about 5,407,498 (292)

Differential Axonal Projection of Mitral and Tufted Cells in the Mouse Main Olfactory System

Frontiers in Neural Circuits, 2010
In the past decade, much has been elucidated regarding the functional organization of the axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli.
Shin Nagayama, Shin Nagayama, Allicia Enerva, Max L Fletcher, Max L Fletcher, Max L Fletcher, Arjun V Masurkar, Kei M Igarashi, Kei M Igarashi, Kensaku Mori, Wei R Chen, Wei R Chen   +11 more
doaj   +1 more source

Double orifice mitral valve associated with Ventricular Septal Defect in an infant : case report [PDF]

, 2011
Double orifice mitral valve (DOMV) is an uncommon anomaly characterized by a mitral valve with a single fibrous annulus with two orifices opening into the left ventricle.
Taksande, Amar M., Thomas, E., Goutami, V.   +2 more
core  

Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve

, 2022
Version 4 du 12 avril 2023 postée sur BioRxivMitral valve prolapse is often associated with several congenital heart malformations. During development, endocardial cells of the atrioventricular canal undergo endothelial to mesenchymal transition (EndMT ...
Michel Pucéat, Simons, Benjamin, Karine Loulier, Farhat, Batoul, Jean Livet, Bordeu, Ignacio, Hugo Blanc, Pucéat, Michel, Batoul Farhat, Loulier, Karine, Livet, Jean, Benjamin D. Simons, Jagla, Bernd, Blanc, Hugo, Ignacio Bordeu, Beaurepaire, Emmanuel, Bernd Jagla, Emmanuel Beaurepaire   +17 more
core   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Collagen Fibrillogenesis in the Mitral Valve: It’s a Matter of Compliance

Journal of Cardiovascular Development and Disease, 2021
Collagen fibers are essential structural components of mitral valve leaflets, their tension apparatus (chordae tendineae), and the associated papillary muscles.
Richard L. Goodwin, Arash Kheradvar, Russell A. Norris, Robert L. Price, Jay D. Potts   +4 more
doaj   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Activity-dependent synaptic competition and dendrite pruning in developing mitral cells

Frontiers in Neural Circuits
During the early postnatal period, neurons in sensory circuits dynamically remodel their connectivity to acquire discrete receptive fields. Neuronal activity is thought to play a central role in circuit remodeling during this period: Neuronal activity ...
Takeshi Imai
doaj   +1 more source

Reciprocal connectivity between mitral cells and external plexiform layer interneurons in the mouse olfactory bulb.

Frontiers in Neural Circuits, 2013
Proper brain function relies on exquisite balance between excitation and inhibition, where inhibitory circuits play fundamental roles towards sculpting principle neuron output and information processing.
Longwen eHuang, Isabella eGarcia, Hsin-I eJen, Benjamin R. Arenkiel   +3 more
doaj   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source