Results 131 to 140 of about 57,584 (249)

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Quantification of Tricuspid Valve Regurgitation With 2D and 4D‐Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly

Journal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 515-523, August 2026.
ABSTRACT Background Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear. Purpose To compare MRI techniques for quantifying
Eric Buffle, Mathieu Albertini, Damian Craiem, Victor Waldmann, Francesca Pitocco, Laurence Iserin, Umit Gencer, Elie Mousseaux, Gilles Soulat   +8 more
wiley   +1 more source

Electrocardiographic Predictors of Cardiac Reverse Remodeling After Left Bundle Branch Area Pacing in Atrioventricular Block: Emphasis on Post‐Pacing QRS Duration

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
In patients with atrioventricular block undergoing left bundle branch area pacing, shorter post‐pacing QRS duration was associated with cardiac reverse remodeling. Post‐pacing QRS duration may represent a simple and clinically applicable electrocardiographic marker for identifying patients more likely to achieve reverse remodeling.
Fahmi Nur Hidayatullah, Giky Karwiky, Mohammad Rizki Akbar, Mohammad Iqbal, Vanny Febriana, Chaerul Achmad   +5 more
wiley   +1 more source

Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease

Echocardiography, Volume 43, Issue 8, August 2026.
Echocardiographic left atrial coupling indexes are promising prognostic markers of dismal outcome in Chagas disease. They were associated with all‐cause mortality independent from age, sex, and echocardiographic indexes, including LV ejection fraction, supporting their potential clinical relevance.
Roberto M. Saraiva, Mauro Felippe F. Mediano, Henrique H. Veloso, Marcelo T. Holanda, Andréa R. Costa   +4 more
wiley   +1 more source

Regurgitation of myxomatous mitral valve: Surgical outcome [PDF]

, 2001
Background. The advantages of mitral valve repair in myxomatous regurgitation are well established. The durability of this reconstructive procedure is variable. The timing of operation is the surgeon dilemma.
GROSSI C, SALA, ANDREA ANTONIO, COZZI G, MANTOVANI, VITTORIO, VANOLI D, ORNAGHI D   +5 more
core  

Clinical and echocardiographic results of the MEMO 4D semi-rigid annuloplasty ring

Journal of Cardiothoracic Surgery
Background Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analyzed the short-term outcomes of mitral valve repair procedures conducted in our clinic using a new semirigid annuloplasty ring featuring a gradual ...
Corrado Fiore, Marcello Melone, Kia Vaziri Farahani, Rebani Sinani, Anna Nicoletti, Luigi Specchia, Giuseppe Santarpino, Giuseppe Speziale   +7 more
doaj   +1 more source

Four‐Chamber Deformation Remodeling and Atrial Fibrillation After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy

Echocardiography, Volume 43, Issue 8, August 2026.
After septal myectomy for hypertrophic obstructive cardiomyopathy, the four chambers of the heart experience unique remodeling patterns that can be visualized with speckle‐tracking strain analysis on echocardiography. This study characterizes those changes and links them to clinical outcomes such as post‐operative atrial fibrillation risk, thereby ...
Olga N. Kislitsina, Lubna Choudhury, Kifah Hussain, James D. Thomas, Seokyung An, Abigail S. Baldridge, Daniel J. Romary, Beth Whippo, James L. Cox, Patrick M. McCarthy, Douglas R. Johnston   +10 more
wiley   +1 more source

Methodological Considerations on Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death

Annals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.
Abdullah Aman, Ahmed Raza, Shahzadi Gulfishan   +2 more
wiley   +1 more source

Impact of the 2025 ASE Updated Recommendations on the Diagnosis of Left Ventricular Diastolic Dysfunction in Asymptomatic Elderly Inpatients With Preserved Ejection Fraction: A Multi‐Center Retrospective Study

Echocardiography, Volume 43, Issue 8, August 2026.
The updated 2025 ASE guidelines achieve more precise evaluation of left ventricular diastolic dysfunction in elderly patients and improve clinical practicality. These guidelines fully abolish the indeterminate diastolic function category that accounted for 12.8% of subjects under the 2016 criteria by reassigning those patients to definite diagnostic ...
Wenwen Chen, Dian Zhang, Yunxiang Miao, Meifang Pan, Yuzhu Miao, Yuping Liao   +5 more
wiley   +1 more source

Mitral valve regurgitation

, 2012
Frank Gaillard, Arlene Campos, Ian Bickle   +2 more
  +4 more sources