Results 241 to 250 of about 55,808 (294)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A hybrid blockchain based deep learning model for multivector attack detection in internet of things enabled healthcare systems. [PDF]

Sci Rep
Sengan S, Shieh CS, Horng MF.
europepmc   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Enhancing the Resilience of ROS 2-Based Multi-Robot Systems with Kubernetes: A Case Study on UWB-Based Relative Positioning. [PDF]

Sensors (Basel)
Zhang J, Yu X, Westerlund T.
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Role of homeostatic plasticity in critical brain dynamics following focal stroke lesions. [PDF]

Sci Rep
Rocha RP, Zorzi M, Corbetta M.
europepmc   +1 more source

Design and Optimization of Mixed-Criticality Systems

, 2016
openaire   +2 more sources

Neurophysiological mechanisms of focused attention meditation: A scoping systematic review. [PDF]

Imaging Neurosci (Camb)
Lieberman JM, McConnell PA, Estarellas M, Sacchet MD.   +3 more
europepmc   +1 more source

Critical dynamics predicts cognitive performance and provides a common framework for heterogeneous mechanisms impacting cognition. [PDF]

Proc Natl Acad Sci U S A
Müller PM, Miron G, Holtkamp M, Meisel C.   +3 more
europepmc   +1 more source

Harnessing Intelligence from Brain Cells In Vitro. [PDF]

Neuroscientist
Kagan BJ, Habibollahi F, Watmuff B, Azadi A, Doensen F, Loeffler A, Byun SH, Servais B, Desouza C, Abu-Bonsrah KD, Kerlero de Rosbo N.   +10 more
europepmc   +1 more source