Results 31 to 40 of about 3,064,284 (141)

Investigations of a compartmental model for leucine kinetics using nonlinear mixed effects models with ordinary and stochastic differential equations

open access: yes, 2011
Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to model non-steady
Adiels, Martin   +4 more
core   +1 more source

Novel Modelling Approaches to Characterize and Quantify Carryover Effects on Sensory Acceptability

open access: yesFoods, 2018
Sensory biases caused by the residual sensations of previously served samples are known as carryover effects (COE). Contrast and convergence effects are the two possible outcomes of carryover.
Damir Dennis Torrico   +5 more
doaj   +1 more source

Bayesian P-Splines to investigate the impact of covariates on Multiple Sclerosis clinical course [PDF]

open access: yes, 2003
This paper aims at proposing suitable statistical tools to address heterogeneity in repeated measures, within a Multiple Sclerosis (MS) longitudinal study.
Di Serio, C., Lamina, C.
core   +1 more source

D-optimal designs formulti-response linear mixed models [PDF]

open access: yes, 2018
Linear mixed models have become popular in many statistical applications duringrecent years. However design issues for multi-response linear mixed models are rarelydiscussed.
Liu, Xin, Wong, Weng Kee, Yue, Rong-Xian
core  

Generalized score test of homogeneity for mixed effects models

open access: yes, 2006
Many important problems in psychology and biomedical studies require testing for overdispersion, correlation and heterogeneity in mixed effects and latent variable models, and score tests are particularly useful for this purpose. But the existing testing
Zhang, Heping, Zhu, Hongtu
core   +2 more sources

A note on Influence diagnostics in nonlinear mixed-effects elliptical models

open access: yes, 2009
This paper provides general matrix formulas for computing the score function, the (expected and observed) Fisher information and the $\Delta$ matrices (required for the assessment of local influence) for a quite general model which includes the one ...
Alexandre G. Patriota   +13 more
core   +1 more source

Consistent Fixed-Effects Selection in Ultra-high dimensional Linear Mixed Models with Error-Covariate Endogeneity

open access: yes, 2020
Recently, applied sciences, including longitudinal and clustered studies in biomedicine require the analysis of ultra-high dimensional linear mixed effects models where we need to select important fixed effect variables from a vast pool of available ...
Ghosh, Abhik, Thoresen, Magne
core   +1 more source

influence.ME: tools for detecting influential data in mixed effects models [PDF]

open access: yes, 2011
influence.ME provides tools for detecting influential data in mixed effects models. The application of these models has become common practice, but the development of diagnostic tools has lagged behind.
Grotenhuis, M. te   +2 more
core   +3 more sources

The relative efficiency of time-to-progression and continuous measures of cognition in presymptomatic Alzheimer's disease. [PDF]

open access: yes, 2019
IntroductionClinical trials on preclinical Alzheimer's disease are challenging because of the slow rate of disease progression. We use a simulation study to demonstrate that models of repeated cognitive assessments detect treatment effects more ...
Aisen, Paul S   +4 more
core   +1 more source

Fitting Linear Mixed-Effects Models Using lme4

open access: yesJournal of Statistical Software, 2015
Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model is described in
Douglas Bates   +3 more
doaj   +1 more source

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