Results 41 to 50 of about 17,397,225 (294)
Operant behavioral economic methods are increasingly used in basic research on the efficacy of reinforcers as well as in large-scale applied research (e.g., evaluation of empirical public policy).
Shawn P. Gilroy +7 more
doaj +1 more source
Simulation-based fully Bayesian experimental design for mixed effects models [PDF]
In this paper, we present fully Bayesian experimental designs for nonlinear mixed effects models, in which we develop simulation-based optimal design methods to search over both continuous and discrete design spaces.
Pettitt, Anthony +5 more
core +2 more sources
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Sequential calibration of material constitutive model using mixed-effects calibration
Identifying model parameters is nowadays intrinsically linked with quantifying the associated uncertainties. While classical methods allow to handle some types of uncertainties such as experimental noise, they are not designed to take into account the ...
Laboulfie Clément +6 more
doaj +1 more source
The linear mixed model has been a major research interest of Dr Arthur Gilmour, motivated by problems arising in research data generated by agricultural scientists.
Thompson, R.
core
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Linguistic pitch analysis using functional principal component mixed effect models [PDF]
Fundamental frequency (F0, broadly 'pitch') is an integral part of spoken human language; however, a comprehensive quantitative model for F0 can be a challenge to formulate owing to the large number of effects and interactions between effects that lie ...
Aston, John A. D. +5 more
core +1 more source

