Results 181 to 190 of about 2,542,204 (245)

Digital Intervention for Electronic Patient-Reported Outcomes in Advanced Cancer: Mixed Methods Study. [PDF]

JMIR Cancer
Sauer C, Sauer S, Doll ES, Zschäbitz S, Raue JS, Turni M, Bugaj TJ, Hiller K, Maatouk I.   +8 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

The Science and Art of Mixed Methods in Medical Education Research. [PDF]

Fam Med
Ledford CJW, Okah E, Tietbohl C.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Digital payments of health workers within vaccination campaigns: a mixed-methods study in Chad. [PDF]

BMJ Glob Health
Bedingar EKN, Wambura C, Osoteku D, Mbailamen AD, Chatte A, Abakar MF, Igbokwe U, Nandoumabe A, Kilone BD, Aina M, McConnell M.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Erratum: Dollar store policy opportunities in Baltimore City: community member and policy maker perspectives

Frontiers in Nutrition
Frontiers Production Office
doaj   +1 more source

Rapid Deployment of Telemedicine in HIV Care: Mixed Methods Study of Providers' Attitudes and Perceptions. [PDF]

J Med Internet Res
Galvin S, Queiroz A, Rivera J, Calamari M, Wright K, Hirschhorn LR, Rusie L, Janulis P, Kumar R, Palella F, Masters MC, Bannon J, Reddy S, Hawkins C.   +13 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Comparative Usability Evaluation of Two Hospital Information Systems: A Mixed-Methods Study in an Iranian Teaching Hospital. [PDF]

Health Sci Rep
Mousavi AS, Jalili Honarvar E, Ardebili Haghighi A, Parveizi S, Granfar M, Mousavi Baigi SF.   +5 more
europepmc   +1 more source