The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
"Assessing inclusiveness in Team Europe Initiatives: a mixed-methods study of EU-Africa health cooperation". [PDF]
Stämmler SL, Viberg N, Bengtsson L.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Adolescents' Strategies to Manage Mental Health Challenges In and After the Pandemic: Two Mixed-Methods Studies. [PDF]
Huizenga HM +4 more
europepmc +1 more source
Exploring Autistic People's Experiences of and Attitudes Towards Cervical Screening: A Mixed-Methods Study. [PDF]
Murdoch S +4 more
europepmc +1 more source
Alignment Between Cardiologists and AI-Driven Diagnostic Systems: Mixed Methods Study. [PDF]
Mahdavi M +5 more
europepmc +1 more source
Analysis of Factors Associated with Stunting in Toddlers: A Mixed Methods Study in Banten, Indonesia. [PDF]
Rukmaini +3 more
europepmc +1 more source
Feasibility and acceptability of ExerciseGuideUK for those living with and beyond lung cancer: a mixed methods study. [PDF]
Curry J +6 more
europepmc +1 more source

