Results 91 to 100 of about 557,317 (281)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Design of Compact Bandpass Filters Using Novel Dual-Mode Dielectric Patch Resonator

open access: yesIEEE Access, 2018
This paper introduces a new dual-mode dielectric patch resonator (DPR), which consists of a thin square dielectric patch with high permittivity and a low-permittivity substrate with bottom ground plane.
Jian-Xin Chen   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Adaptive Event-Triggered Mixed $H_{\infty}$ and Passivity-Based Filter Design for Nonlinear T-S Fuzzy Markovian Switching Systems With Time-Varying Delays

open access: yesIEEE Access, 2019
This paper discusses the problem of mixed H∞ and passivity-based filter design for non-linear T-S Fuzzy Markovian Switching Systems (F-MSSs) with time-varying delays, under the adaptive event-triggered scheme. At first, an adaptive event-triggered
Muhammad Shamrooz Aslam   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

DESIGN AND STABILITY ANALYSIS OF MIXED-MODE FILTERS CONTAINING ONLY GROUNDED CAPACITORS

open access: yesJournal of Circuits, Systems and Computers, 2010
In this paper, three dual-mode (mixed-mode) analog filters using only grounded capacitors and two to three second-generation current conveyors (CCIIs) are presented. The first proposed filter can provide a transimpedance-mode (TIM) second-order filter transfer function (TF), and is free from passive component matching constraints, which is ...
Yüce, Erkan, Tokat, Sezai
openaire   +3 more sources

Implementation of IMMPDAF Algorithm in LabVIEW for Multi Sensor Single Target Tracking [PDF]

open access: yes, 2008
Real time IMMPDAF algorithm has been implemented and tested in LabVIEW. Single aircraft flight profiles have been simulated and the plot data from multiple radars observing the single aircraft are generated with noise as well as clutter. The performance
Girija, G, Naidu, VPS
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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