Results 211 to 220 of about 4,674,587 (322)

Sex-specific exploration accounts for differences in valence learning in male and female mice. [PDF]

Elife
Schuler H, Iyer ES, Siemonsmeier G, Weinbaum AM, Vitaro P, Shen S, Bagot RC.   +6 more
europepmc   +1 more source

Privacy Preserving Diffusion Models for Mixed-Type Tabular Data Generation [PDF]

Timur Sattarov, Marco Schreyer, Damian Borth   +2 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Estimating Endmember Backscattering Coefficients Within the Mixed Pixels Based on the Microwave Backscattering Contribution Decomposition Model. [PDF]

Sensors (Basel)
Song Y, Zhang Z, Zheng H, Hou X, Lei J, Gao X, Hellwich O.   +6 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Postprandial Glucagon Metabolism in Healthy and Type 1 Diabetes. [PDF]

Diabetes
Ruchi FNU, Schiavon M, Pandey A, Dalla Man C, Cobelli C, Basu R, Basu A.   +6 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Histomorphological development and progression of gastric intramucosal papillary adenocarcinoma-a retrospective study. [PDF]

Front Oncol
Wang YK, Zou XF, Wang WY, Li YY, Zhong Y, Guo P, Wang T, Xu SL, Wang SN.   +8 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The rare report of unicentric Castleman disease with concurrent myasthenia gravis and paraneoplastic pemphigus: a case report with a focused review of the literature. [PDF]

Front Oncol
Cheng Z, Liu W, Hu Y.
europepmc   +1 more source