Results 101 to 110 of about 8,840,706 (291)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Effects of Supplementation with Powder from Various Medicinal Plants on Productivity and Quality of Eggs from Laying Hens

open access: yesRevista de Producción Animal, 2018
To evaluate the effect of feed supplementation based on a mixture of from medicinal plants powder (40 % Psidium guajava L.; 20 % Morinda citrifolia L.) on production and quality of eggs from laying hens, 160 White Leghorn hybrid hens (L-33), 27 weeks old,
Ivonne Salazar Bell   +7 more
doaj  

AI-Enhanced Wide Supply Voltage Bandgap Voltage Reference Circuit With Multi-Objective Optimization for Automotive Applications

open access: yesIEEE Open Journal of Circuits and Systems
This paper presents a bandgap voltage reference (BGR) circuit with a wide supply voltage and temperature range, suitable for automotive applications.
U Chi-Wa   +4 more
doaj   +1 more source

Natural discharge after pulse and cooperative electrodes to enhance droplet velocity in digital microfluidics

open access: yesAIP Advances, 2014
Digital Microfluidics (DMF) is a promising technology for biological/chemical micro-reactions due to its distinct droplet manageability via electronic automation, but the limited velocity of droplet transportation has hindered DMF from utilization in ...
Tianlan Chen   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An Overview of Hybrid DC–DC Converters: From Seeds to Leaves

open access: yesIEEE Open Journal of the Solid-State Circuits Society
With the surging demands for higher current at sub-1-V supply level in high-performance digital systems, high-efficiency and high-current-density power converters are essential for system integration.
Yan Lu   +7 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

George Meade’s Mixed Legacy

open access: yes, 2013
George Gordon Meade was 47 years old the morning of June 28, 1863, when command of the Army of the Potomac was unceremoniously dumped into his lap by General in Chief Henry Hallcck, and there is no reason to doubt Meade\u27s protest that the move ...
Guelzo, Allen C.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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