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Mixed connective tissue disease
Clinics in Dermatology, 1985Abstract Mixed connective tissue disease (MCTD) was first described by Gordon Sharp, 1 in 1972, as a distinct connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and dermato/polymyositis (DP/PM).
D T, Schreiner, J L, Jorizzo
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Mixed Connective Tissue Disease
Current Opinion in Rheumatology, 2000A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in murine models of disease.
R W, Hoffman, E L, Greidinger
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Mixed Connective-Tissue Disease
New England Journal of Medicine, 1977Coping with chronic illness has become a personal experience for me. For the past 13 years, I have gone through various stages of coping with mixed connective tissue disease (MCTD), a rare collagen-vascular disease of unknown origin that resembles scleroderma, lupus erythematosus, and polymyositis.
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Mixed connective tissue disease
Best Practice & Research Clinical Rheumatology, 2016The concept of mixed connective tissue disease (MCTD) as a separate connective tissue disease (CTD) has persisted for more than four decades. High titers of antibodies targeting the U1 small nuclear ribonucleoprotein particle (U1 snRNP) in peripheral blood are a sine qua non for the diagnosis of MCTD, in addition to distinct clinical features including
Ragnar, Gunnarsson +3 more
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Pediatric Mixed Connective Tissue Disease
Current Rheumatology Reports, 2016Pediatric-onset mixed connective tissue disease is among the rare disease entities in pediatric rheumatology and includes features of arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, and systemic sclerosis. Accurate recognition and diagnosis of the disease is paramount to prevent long-term morbidity.
Roberta A, Berard, Ronald M, Laxer
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Mixed connective tissue disease
Lupus, 2006Mixed connective tissue disease (MCTD) was first described in 1972 as a disease syndrome with overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE) and polymyositis associated with antibodies to RNAse sensitive extractable nuclear antigen.
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Mixed Connective Tissue Disease
2008Mixed connective tissue disease (MCTD) is a condition characterized by the overlap of features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polydermatomyositis (PM/DM) in association with high titers of antibodies against a ribonuclear protein (RNP).
MOSCA, MARTA +2 more
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Mixed Connective Tissue Disease
Radiologic Clinics of North America, 1988MCTD is characterized by clinical features that overlap those of several of the classic rheumatic and connective tissue disorders. Although MCTD has been distinguished from them by the presence of antibodies to an RNP and by specific immunoregulatory T cell circuit abnormalities, its definitive placement among the classic disorders remains ...
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Mixed connective tissue disease revisited
Clinical Rheumatology, 1982SCOPUS: ar.j ; info:eu-repo/semantics ...
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