Results 51 to 60 of about 136,094 (289)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

OVERLAP IN CONNECTIVE TISSUE DISEASES EVALUATION OF 119 CASES [PDF]

Acta Medica Iranica, 1998
The overlap syndrome is a vague entity in the, group of connective tissue diseases. It is unclear whether it is fortuitous association of two or more connective tissue diseases (C'l'D). or a distinct disease.
S.G. Soroosh., F. Shahram., M. Akbarian., F. Gharibdoost., A. Nadji., A. Jamshidi F. Davatchi   +5 more
doaj   +2 more sources

An uncommon manifestation of mixed connective tissue disorder presenting as dilated cardiomyopathy

Heart India
Mixed connective tissue disorder is a systemic autoimmune disorder that can affect any organ in the system including the heart. Varied cardiac manifestation of mixed connective tissue disease has been reported including pericarditis, pulmonary ...
Ashok Jain
doaj   +1 more source

Association Between Type B Insulin Resistance Syndrome and Mixed Connective Tissue Disease in an Arab African Man

Oman Medical Journal, 2020
Type B insulin resistance syndrome (TBIRS) has not been previously reported in Arab populations. We report a case of TBIRS in an Arab patient with mixed connective tissue disease (MCTD).
Khaled Aburisheh, Yousuf Al Farsi, Fauzia Moyeen, Faryal Mehmood   +3 more
doaj   +1 more source

Predisposition of HLA-DRB1*04:01/*15 heterozygous genotypes to Japanese mixed connective tissue disease

Scientific Reports, 2022
Mixed connective tissue disease (MCTD) is a rare systemic autoimmune disease characterized by the production of anti-U1 ribonucleoprotein antibodies and systemic symptoms similar to those of some other autoimmune diseases.
Shomi Oka, Takashi Higuchi, Hiroshi Furukawa, Kota Shimada, Atsushi Hashimoto, Akiko Komiya, Toshihiro Matsui, Naoshi Fukui, Eiichi Suematsu, Shigeru Ohno, Hajime Kono, Masao Katayama, Shouhei Nagaoka, Kiyoshi Migita, Shigeto Tohma   +14 more
doaj   +1 more source

Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

Oman Medical Journal, 2022
Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus ...
Talal Al Lawati, Batool Hassan
doaj   +1 more source

Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]

, 2016
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M, Llado, A, Paolino, S, Pizzorni, C, Ruaro, B, Smith, Vanessa, Sulli, A   +6 more
core   +1 more source

Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects [PDF]

, 2013
Mesenchymal stem cells (MSCs) are able to infiltrate tumor tissues and thereby effectively deliver gene therapeutic payloads. Here, we engineered murine MSCs (mMSCs) to express a secreted form of the TNF-related apoptosis-inducing ligand (TRAIL), which ...
A Ashkenazi, A Ashkenazi, A Chuntharapai, A Mohr, A Mohr, A Mohr, A Mohr, A Nakamizo, A Peister, AM van der Sloot, B Hall, C Buneker, CR Reis, D Sampath, D Stadel, DR Camidge, EW Duiker, FP Barry, GS Wu, GS Wu, I Nicoletti, J Lemke, J Luetzkendorf, JW Schymkowitz, K Ichikawa, K Papenfuss, L Zhang, LG Menon, LS Sasportas, M MacFarlane, M Vogler, M Vogler, M Vogler, ME Davis, MH Kim, MR Loebinger, MR Sprick, RM Zwacka, RW Johnstone, SB Bratton, SJ Braeuer, SM Albarenque, SM Kim, T Trarbach, TK Oost, TM Ganten, TS Griffith   +46 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]

, 2017
BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria, Amoroso, Antonio, Barbano, Biagio, Cianci, Rosario, Gigante, Antonietta, Margiotta, Domenico, Navarini, Luca, Rosato, Edoardo   +7 more
core   +1 more source