Results 51 to 60 of about 154,355 (274)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On Designing Mixed EWMA Dual-CUSUM Chart With Applications in Petro-Chemical Industry
IEEE Access, 2018 In recent times, the trending modification of control chart is a result of its effective application in various aspects of life. In this paper, we propose a new charting scheme called mixed exponentially weighted moving average (EWMA) dual-cumulative sum
Nasir Abbas +3 more
doaj +1 more source
Research on Quality Anomaly Recognition Method Based on Optimized Probabilistic Neural Network
Shock and Vibration, 2020 Aiming at the problems of the lack of abnormal instances and the lag of quality anomaly discovery in quality database, this paper proposed the method of recognizing quality anomaly from the quality control chart data by probabilistic neural network (PNN)
Li-li Li, Kun Chen, Jian-min Gao, Hui Li
doaj +1 more source
Case-mix and the use of control charts in monitoring mortality rates after coronary artery bypass [PDF]
BMC Health Services Research, 2007 Abstract Background There is debate about the role of crude mortality rates and case-mix adjusted mortality rates in monitoring the outcomes of treatment. In the context of quality improvement a key purpose of monitoring is to identify special cause variation as this type of variation should be investigated to identify ...
Mohammed Mohammed A, Marshall Tom
openaire +3 more sources
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Application of SPC in Short Run and Small Mixed Batch Production: Case of Bakery Equipment Producer
Kvalita Inovácia Prosperita, 2018 Purpose: The purpose of this paper is to present preliminary research in statistical process control (SPC) of short run and small mixed batches (SR-SMB) at the organization producing bakery equipment.
Darina Juhászová
doaj +1 more source