Results 241 to 250 of about 5,633 (293)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Failure in a population: Tauopathy disrupts homeostatic set-points in emergent dynamics despite stability in the constituent neurons. [PDF]

Neuron
McGregor JN, Farris CA, Ensley S, Schneider A, Fosque LJ, Wang C, Tilden EI, Liu Y, Tu J, Elmore H, Ronayne KD, Wessel R, Dyer EL, Bhaskaran-Nair K, Holtzman DM, Hengen KB.   +15 more
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Atypical pulmonary tuberculosis and haemophilus influenzae co-infection presenting as refractory postpartum fever: Diagnostic utility of next-generation sequencing. [PDF]

IDCases
Xiang Y, Xiong B, Qin L, Xu H.
europepmc   +1 more source

Assessing the Impact of CDR Deamidation and Isomerization on mAb Target Binding Using Affinity-Resolved 2D-SEC-SCX-MS Analysis. [PDF]

J Am Soc Mass Spectrom
Yan Y, Tang S, Wang S, Li N.
europepmc   +1 more source

Multi-organoid loop cerebral connectoids exhibit enhanced neuronal network dynamics and sequence-specific entrainment. [PDF]

Commun Biol
Duenki T, Ikeuchi Y.
europepmc   +1 more source

Optimizing concrete pump maintenance in the construction sector using enhanced MCDM techniques. [PDF]

Sci Rep
Deepak D, Brar GS, Dwivedi S, Farwaha HS, Ranjan N, Alkhaleel BA, Pandey S.   +6 more
europepmc   +1 more source

Protocol for a multicenter prospective sequential intervention study: the effect of adaptive closed-loop postural training on gait disorders in hemiparetic stroke patients. [PDF]

Front Neurol
Zhou L, Li J, Xu Y, Kang X, Li J, Liang B, Chen B, Guo Q, Zhang X, Wang Z, Huang T, Xu M, Bao Z, Abdul Rahim NA, Hou Y, Yusof HA.   +15 more
europepmc   +1 more source

Amplified multipartite entanglement witnessed in a quantum critical metal. [PDF]

Nat Commun
Fang Y, Mahankali M, Wang Y, Chen L, Hu H, Paschen S, Si Q.   +6 more
europepmc   +1 more source