Results 61 to 70 of about 306,618 (310)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2018 Herein, we explored a simple metal–organic framework (MOF)-mediated synthesis for the controlled preparation of pure and mixed-phase titania (TiO2) nanoparticles.
Christopher P. Ireland (1275237) +13 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Application of a Single-Crystal CVD Diamond Detector for Fast Neutron Measurement in High Dose and Mixed Radiation Fields [PDF]
ORCID 0000-0002-6250-4349This article presents the method to evaluate the fast neutron energy spectrum using the single-crystal chemical vapor deposition (CVD) diamond detector to be applicable on the radiation monitoring in advanced scientific ...
KOBAYASHI, Makoto I. +13 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Curvilinear triangular-prism element for computation of band structure in photonic crystal slab [PDF]
, 2006 The band structure of a photonic crystal slab is analyzed by the finite-element method. Here, a curvilinear mixed-interpolation-type triangular-prism element is proposed so as to express cylindrical air holes of a photonic crystal slab smoothly enough in
Tsuji, Yasuhide +3 more
core +1 more source
Advances in Materials Science and Engineering, 2014 The strength of the cement-stabilized soil can be improved by the use of seawater. Compressive strength test results show that the strength of cement-stabilized soil mixed with seawater is 50% greater than that mixed with freshwater at the 90th day ...
Qiang Li +3 more
doaj +1 more source
Crystal structure of the mixed-metal thiophosphate Nb1.18V0.82PS10
Acta Crystallographica Section E: Crystallographic Communications, 2015 The mixed-metal thiophosphate, Nb1.18V0.82PS10 (niobium vanadium phosphorus decasulfide), has been prepared though solid state reactions using an alkali-metal halide flux. The title compound is isostructural with two-dimensional Nb2PS10.
Joobin Sun, Jiyun Heo, Hoseop Yun
doaj +1 more source