Results 91 to 100 of about 969,174 (273)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Do Graph Readers Prefer the Graph Type Most Suited to a Given Task? Insights from Eye Tracking

open access: yesJournal of Eye Movement Research, 2016
Research on graph comprehension suggests that point differences are easier to read in bar graphs, while trends are easier to read in line graphs. But are graph readers able to detect and use the most suited graph type for a given task?
Benjamin Strobel   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A Cellular Automata Traffic Flow Model considering Bus Lane Changing Behavior with Scheduling Parameters

open access: yesDiscrete Dynamics in Nature and Society, 2015
According to different driving behavioral characteristics of bus drivers, a cellular automata traffic model considering the bus lane changing behavior with scheduling parameters is proposed in this paper.
Zun-dong Zhang   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

On spectra of unitary Cayley mixed graph [PDF]

open access: yesTransactions on Combinatorics, 2016
‎‎‎‎In this paper we introduce mixed unitary Cayley graph $M_{n}$‎ ‎$(n>1)$ and compute its eigenvalues‎. ‎We also compute the energy of‎ ‎$M_{n}$ for some $n$‎.
Chandrashekar Adiga   +1 more
doaj  

On bipartite (1,1,k)-mixed graphs

open access: yesThe Art of Discrete and Applied Mathematics
Mixed graphs can be seen as digraphs with arcs and edges (or digons, that is, two opposite arcs). In this paper, we consider the case where such graphs are bipartite and in which the undirected and directed degrees are one. The best graphs, in terms of the number of vertices, are presented for small diameters.
Dalfó Simó, Cristina   +4 more
openaire   +5 more sources

Consistency of adjacency spectral embedding for the mixed membership stochastic blockmodel

open access: yes, 2017
The mixed membership stochastic blockmodel is a statistical model for a graph, which extends the stochastic blockmodel by allowing every node to randomly choose a different community each time a decision of whether to form an edge is made.
Priebe, Carey E.   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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