Results 81 to 90 of about 3,087,593 (348)
Discrete Mathematics, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dourado, Mitre C. +4 more
openaire +2 more sources
Approximation algorithms for orienting mixed graphs [PDF]
Theoretical Computer Science, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Elberfeld, Michael +4 more
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
On Mixed Metric Dimension of Some Path Related Graphs
IEEE Access, 2020 A vertex $k\in V_{G}$ determined two elements (vertices or edges) $\ell,m \in V_{G}\cup E_{G}$ , if $d_{G}(k,\ell)\neq d_{G}(k,m)$ . A set $R_ {\text {m}}$ of vertices in a graph $G$ is a mixed metric generator for $G$ , if two distinct elements
Hassan Raza, Ying Ji, Shaojian Qu
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A Graph Theoretic Perspective on CPM(Rel) [PDF]
Electronic Proceedings in Theoretical Computer Science, 2015 Mixed states are of interest in quantum mechanics for modelling partial information. More recently categorical approaches to linguistics have also exploited the idea of mixed states to describe ambiguity and hyponym / hypernym relationships.
Daniel Marsden
doaj +1 more source
Electronic Notes in Discrete Mathematics, 2014 Cayley graphs are well known objects with interesting properties, also in the context of Moore graphs and digraphs. In $1978$ Bos\'ak extended Moore's property to the mixed setting (with arcs allowed along with edges), in the so called mixed Moore graphs: those having a unique trail--path?
López Lorenzo, Ignacio +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Improved Approximation for Orienting Mixed Graphs [PDF]
Algorithmica, 2012 An instance of the maximum mixed graph orientation problem consists of a mixed graph and a collection of source-target vertex pairs. The objective is to orient the undirected edges of the graph so as to maximize the number of pairs that admit a directed source-target path.
Gamzu, Iftah, Medina, Moti
openaire +4 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source