Results 81 to 90 of about 969,174 (273)
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Dourado, Mitre C. +4 more
openaire +2 more sources
Approximation algorithms for orienting mixed graphs [PDF]
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Elberfeld, Michael +4 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A Graph Theoretic Perspective on CPM(Rel) [PDF]
Mixed states are of interest in quantum mechanics for modelling partial information. More recently categorical approaches to linguistics have also exploited the idea of mixed states to describe ambiguity and hyponym / hypernym relationships.
Daniel Marsden
doaj +1 more source
Cayley graphs are well known objects with interesting properties, also in the context of Moore graphs and digraphs. In $1978$ Bos\'ak extended Moore's property to the mixed setting (with arcs allowed along with edges), in the so called mixed Moore graphs: those having a unique trail--path?
López Lorenzo, Ignacio +2 more
openaire +2 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
m-step inverse fuzzy mixed competition graphs
The notion of competition graphs has a wide range of applications and has been utilized in designing various ecological problems and real-world competitions.
Rahul Mondal, Ganesh Ghorai
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source

