Results 61 to 70 of about 1,771,812 (257)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Semigroup Forum, 1997 Let \(G\) be a totally minimal group, i.e., there does not exist a strictly coarser Hausdorff group topology on \(G\). The author associates to any representation on \(G\) an enveloping semigroup that is weakly almost periodic; hence semigroup theory may be used.
openaire +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
SAGE Open, 2020 Despite increased diversity on campuses worldwide, research has documented a lack of intercultural interaction among university students. Culturally mixed groups have been found to be a promising means of promoting the rich, repeated contact necessary ...
Shu-Wen Lan
doaj +1 more source
Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands. [PDF]
Clin Proteomics, 2023 Musiał N +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Making Sense of Facebook: A Mixed Methods Approach to Analysing Online Student Groups
Seminar.net, 2015 The objective of this paper is to discuss a methodological design developed to analyse self-governed student Facebook groups as a part of a larger study of the use of ICT in Danish secondary schools (Mathiasen. Aaen, Dalsgaard, Degn & Thomsen, 2014). The
Janus Aaen
doaj
Clinical leadership in service redesign using Clinical Commissioning Groups: a mixed-methods study
Health Services and Delivery Research, 2018 Background: A core component of the Health and Social Care Act 2012 (Great Britain. Health and Social Care Act 2012. London: HMSO; 2012) was the idea of devolving to general practitioners (GPs) a health service leadership role for service redesign.
John Storey +4 more
doaj +1 more source
MIXING FOR PROGRESSIONS IN NONABELIAN GROUPS [PDF]
Forum of Mathematics, Sigma, 2013 AbstractWe study the mixing properties of progressions $(x, xg, x{g}^{2} )$, $(x, xg, x{g}^{2} , x{g}^{3} )$ of length three and four in a model class of finite nonabelian groups, namely the special linear groups ${\mathrm{SL} }_{d} (F)$ over a finite field $F$, with $d$ bounded. For length three progressions $(x, xg, x{g}^{2} )$, we establish a strong
openaire +4 more sources