Results 71 to 80 of about 3,434,361 (250)

A Comprehensive in Silico Analysis of Regulatory SNPs of Human CLEC7A Gene and Its Validation as Genotypic and Phenotypic Disease Marker in Recurrent Vulvovaginal Infections

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Recurrent Vulvovaginal infections (RVVI) are the commonly reported microbiological syndrome affecting millions of women globally. Various molecules of innate immune system are instrumental in clearance of these microbial pathogens, thus suggested as one ...
Namarta Kalia   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Multiple bovine papillomavirus infections associated with cutaneous papillomatosis in brazilian cattle herds

open access: yesBrazilian Archives of Biology and Technology, 2009
Cutaneous papillomatosis is a pathological condition commonly found in cattle and is characterized by the presence of benign proliferative tumors caused by bovine papillomavirus (BPV) infection.
Marlise Pompeo Claus   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The dynamics of natural Plasmodium falciparum infections. [PDF]

open access: yes, 2012
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on parasite dynamics are poorly understood. Acquisition and clearance rates of untreated infections are key elements of the dynamics of malaria, but estimating
Ingrid Felger (92160)   +44 more
core   +1 more source

Other title: Healthcare Associated Infections annual report; Other title: Report to the legislature concerning the status of the Healthcare Associated Infections Initiative

open access: yes, 2015
Annual; Began with Oct. 1, 2008.; "An Act Concerning Hospital Acquired Infections."; At head of title: State of Connecticut.; Volume for Oct.
Healthcare Associated Infections Program (Conn.)
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

АССОЦИАТИВНЫЕ ЖЕЛУДОЧНО-КИШЕЧНЫЕ ИНФЕКЦИИ МОЛОДНЯКА СВИНЕЙ В РОСТОВСКОЙ ОБЛАСТИ

open access: yesВетеринарная патология, 2010
Mixed gastro-intestinal infections of young swines are registered more often for the last years. The analysis of microbe associations found in swine farms of Rostov District allows to come to the conclusion that the major etiological agents with given ...

doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Other title: Healthcare Associated Infections annual report; Other title: Report to the legislature concerning the status of the Healthcare Associated Infections Initiative

open access: yes, 2018
Annual; Began with Oct. 1, 2008.; "An Act Concerning Hospital Acquired Infections."; At head of title: State of Connecticut.; Volume for Oct.
Healthcare Associated Infections Program (Conn.)
core   +1 more source

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