Results 81 to 90 of about 604,878 (242)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Sensory analysis of Prato cheeses by generalized linear mixed models
Revista do Instituto de Latícinios Cândido TostesSensory analysis, an area of Food Science, is used to analyze and measure characteristics of foods, being able to evaluate the acceptance of samples. Such assessments can be performed using the 9-point numerical hedonic scale, classified as an ordinal ...
Tatiane Carvalho Alvarenga +1 more
doaj +1 more source
Application of Mixed Linear Models in the Analysis of Road Surface Features
Lithuanian Journal of Statistics, 2015 The data were collected by researchers at the Road Research Institute, in a study investigating the impact of differentfactors on road surface strength.
Jurgita Židanavičiūtė +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Congruency of Separable Affix Verb Combinations Is Linearly Indexed by the N400
Frontiers in Human Neuroscience, 2018 Separable affix verbs consist of a stem and a derivational affix, which, in some languages can appear together or in discontinuous, distributed form, e.g., German “aufgreifen” and “greifen … auf” [“up-pick(ing)” and “pick … up”].
Jeff Hanna +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Neighborhood-level heterogeneity in childhood morbidity through generalized linear mixed models
Frontiers in Public HealthObjectiveChildhood morbidities are crucial for improving long-term public health outcomes. This study aimed to examine the existence of child-specific and regional variation in childhood morbidity based on the cross-cutting study of the Performance ...
Endeshaw A. Derso +8 more
doaj +1 more source
Genetics Selection Evolution, 2005 We propose a general Bayesian approach to heteroskedastic error modeling for generalized linear mixed models (GLMM) in which linked functions of conditional means and residual variances are specified as separate linear combinations of fixed and random ...
Kizilkaya Kadir, Tempelman Robert J
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Precise asymptotics for linear mixed models with crossed random effects
Statistical Theory and Related FieldsWe obtain an asymptotic normality result that reveals the precise asymptotic behaviour of the maximum likelihood estimators of parameters for a very general class of linear mixed models containing cross random effects.
Jiming Jiang +2 more
doaj +1 more source