Results 171 to 180 of about 32,627,451 (335)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Hidden Impact of Cyberbullying on Teens' Orthodontic Decisions: A Mixed-Methods Study. [PDF]

J Clin Exp Dent
Sonwane S, Sonwane S, Awasthi P.
europepmc   +1 more source

Hospitality Students’ Knowledge, Attitudes, and Readiness for Sexual Harassment Prevention in Ghana: Mixed-Methods Dataset (2024–2025)

Afful, Ebenezer Junior
openalex   +1 more source

Feasibility and acceptability of offering breast cancer risk assessment to general population women aged 30–39 years: a mixed-methods study protocol [PDF]

Sarah Hindmarch, Sacha J. Howell, Juliet A. Usher‐Smith, Louise Gorman, D. Gareth Evans, David French   +5 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Nursing management decisions in fever: a mixed-methods approach to understanding. [PDF]

Int J Nurs Stud Adv
Chen LA, Fawcett TN, Chandler C, Weng TW.   +3 more
europepmc   +1 more source

A mixed-methods-evaluation approach for the study of macro-micro interactions: on the development of teaching- and learning-oriented beliefs of mathematics student teachers in the introductory phase of study

, 2017
Nils Buchholtz, Gabriele Kaiser
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Enhancing nurses' psychological empowerment through NLP: a mixed-methods study. [PDF]

BMC Nurs
Şen Olgay S, Uğur E.
europepmc   +1 more source

Family group conference provision across the lifespan of child welfare intervention: A mixed-method realist-informed evaluation, comparing three stages of welfare concern

Lee Sobo-Allen, Lois Liao, Jonathan Scourfield, Felicity Smith, Sophie Wood, Melissa Meindl, Kar Man Au, Abigail Palmer, Rhiannon Evans, Fiona Lugg‐Widger, Tarirai Lincoln Mahachi, Philip Pallmann, Stavros Petrou, Mike Robling, Elizabeth-Ann Schroeder, David Wilkins   +15 more
openalex   +1 more source