Results 51 to 60 of about 3,384,887 (243)

Elasticity tetrads, mixed axial-gravitational anomalies, and (3+1)-d quantum Hall effect

Physical Review Research, 2019
For two-dimensional topological insulators, the integer and intrinsic (without external magnetic field) quantum Hall effect is described by the gauge anomalous (2+1)-dimensional [(2+1)-d] Chern-Simons (CS) response for the background gauge potential of ...
J. Nissinen, G. E. Volovik
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Novel Minkowski-Based Fractal Analysis Framework for EEG: Theory and Application in Alzheimer’s Detection

Fractal and Fractional
Existing electroencephalography (EEG) complexity methods treat channels as independent univariate series under an isotropic Euclidean metric, which retains the magnitude of inter-channel fluctuations but not the direction of interhemispheric dominance ...
İpek Ebru Karaçay, Salim Yüce
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Mixed Partition Dimension: A New Resolvability Parameter in Graph Theory

IEEE Access
In this article, we introduce a novel graph-theoretical parameter called the mixed partition dimension and apply it to the path graph and the hexagonal network.
Siti Norziahidayu Amzee Zamri, Sikander Ali, Muhammad Azeem, Husam A. Neamah, Bandar Almohsen   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

THE ROLE OF ARTIFICIAL INTELLIGENCE IN ASSESSING THE REVENUE MANAGEMENT EFFECTIVENESS

Agora International Journal of Economical Sciences
This paper develops and evaluates an organizational mechanism for AI-enhanced revenue management (RM) in hospitality that combines monitoring and analytics, machine-learning-driven dynamic pricing, advanced AI segmentation, strategic partnerships, and ...
Margaryta Boiko, Myroslava Bosovska, Mariia Kulyk, Nadiia Vedmid   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Critical reading and the structure of institutional academic performance: evidence from Colombia's Saber 11 examination

Frontiers in Education
Large-scale assessments provide important evidence on educational performance, but institution-level results may provide an incomplete picture when academic domains are interpreted as independent indicators or simple ordinal comparisons.
Oswaldo Plata-Pineda, Fabián A. González-López, Miguel H. Guamanga   +2 more
doaj   +1 more source