Results 61 to 70 of about 3,254,426 (235)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
THE ROLE OF ARTIFICIAL INTELLIGENCE IN ASSESSING THE REVENUE MANAGEMENT EFFECTIVENESS
Agora International Journal of Economical SciencesThis paper develops and evaluates an organizational mechanism for AI-enhanced revenue management (RM) in hospitality that combines monitoring and analytics, machine-learning-driven dynamic pricing, advanced AI segmentation, strategic partnerships, and ...
Margaryta Boiko +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the metric dimension of infinite graphs [PDF]
, 2012 A set of vertices S resolves a graph G if every vertex is uniquely determined by its vector of distances to the vertices in S. The metric dimension of a graph G is the minimum cardinality of a resolving set. In this paper we study the metric dimension of
Hernando, C. +4 more
core +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Metric mean dimension and mean Hausdorff dimension varying the metric [PDF]
Let $f: M\rightarrow M$ be a continuous map on a compact metric space $M$ equipped with a fixed metric $d$, and let $τ$ be the topology on $M$ induced by $d$.
Acevedo, Jeovanny Muentes +3 more
core +3 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The CAT(0) dimension of 3-generator Artin groups
, 2002 The three generator Artin groups A(m,n.2) are known to be have CAT(O) dimension strictly greater than two if both m and n are odd [BC]. In Chapter 1 we introduce the notions of CAT(O) dimension and three generator Artingroups.In Chapter 2 we show that if
Hanham, Paul Edward
core +1 more source
Fractal and FractionalUsing 48 shale samples from the lower member of the Longmaxi Formation in Well YL, in the Middle Yangtze region, we investigate the fractal characteristics of pore structures across different shale lithofacies based on total organic carbon (TOC), X-ray ...
Yi Sun +3 more
doaj +1 more source