Results 81 to 90 of about 25,129 (234)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
SMARANDACHE MULTI-SPACE THEORY, Second Edition [PDF]
, 2011 We are used to the idea that our space has three dimensions: length, breadth and height with time providing the fourth dimension of spacetime by Einstein. In the string or superstring theories, we encounter 10 dimensions.
MAO, Linfan
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Diophantine approximation: the twisted, weighted and mixed theories [PDF]
, 2011 This PhD thesis consists of five papers dealing with problems in various branches of Diophantine approximation. The results obtained contribute to the theory of twisted, weighted, multiplicative and mixed approximation.
Harrap, S., Harrap, Stephen
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Dynamic Time Warping as Elementary Effects Metric for Morris-Based Global Sensitivity Analysis of High-Dimension Dynamical Models [PDF]
This work focused on demonstrating the use of dynamic time warping (DTW) as a metric for the elementary effects computation in Morris-based global sensitivity analysis (GSA) of model parameters in multivariate dynamical systems.
Ashley P. Mikolajczyk +7 more
core +1 more source
Metric Based Upscaling for Partial Differential Equations with a Continuum of Scales [PDF]
, 2007 Numerical upscaling of problems with multiple scale structures have attracted increasing attention in recent years. In particular, problems with non-separable scales pose a great challenge to mathematical analysis and simulation.
Zhang, Lei
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Coarse group theoretic study on stable mixed commutator length [PDF]
, 2023 Let $G$ be a group and $N$ a normal subgroup of $G$. We study the large scale behavior, not the exact values themselves, of the stable mixed commutator length $scl_{G,N}$ on the mixed commutator subgroup $[G,N]$; when $N=G$, $scl_{G,N}$ equals the stable
Maruyama, Shuhei +4 more
core +1 more source