Results 51 to 60 of about 1,992,399 (301)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Lifetime evaluation of concrete structures under sustained post-peak loading [PDF]

open access: yes, 2005
Experimental tests on crack propagation in concrete under constant post-peak loading are simulated using the finite element method and the cohesive crack model, in both Mode I and Mixed-mode conditions.
Barpi, Fabrizio, Valente, Silvio
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Mapping Real-World Data to Self-Reported Information to Explore Determinants of Location Selection for Community Pharmacies in Taiwan

open access: yesJournal of Multidisciplinary Healthcare, 2023
Jie Chen,1,* Yen-Ming Huang,1– 3,* Hsun-Yu Chan,4 Mon-Chiao Chen,5 Yunn-Fang Ho1,2 1School of Pharmacy, College of Medicine, National Taiwan University, Taipei, 100025, Taiwan; 2Graduate Institute of Clinical Pharmacy, College of Medicine ...
Chen J   +4 more
doaj  

Missing mixed mode: elemental structures

open access: yesRevista Obets, 2012
One of the main concerns is the nature of the missing values. Let’s consider extremes for simplicity. If missing at random we have not to care about.
Antonio Alaminos Chica
doaj   +1 more source

Residual strength evaluation under mixed mode loading [PDF]

open access: yesMATEC Web of Conferences, 2019
This work explores the failure resistance of fatigue damages with random orientation through a new computational framework. Such analytical model aims to enable designers to properly and quickly assess stress state and residual life under cyclic loading ...
Boljanović Slobodanka   +2 more
doaj   +1 more source

Mixed-mode multicore reliability [PDF]

open access: yes, 2009
Future processors are expected to observe increasing rates of hardware faults. Using Dual-Modular Redundancy (DMR), two cores of a multicore can be loosely coupled to redundantly execute a single software thread, providing very high coverage from many ...
Gurindar S. Sohi   +2 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Mixed Mode Crack Propagation in Iliac Bone

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2021
Bone is a complex material that can be regarded as an anisotropic elastic composite material. The problem of crack propagation in human bone is analyzed by using a generalization of the maximum tensile stress criterion (MTS).
Baesu E.   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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