Results 61 to 70 of about 1,828,929 (311)

The Mixed Assessor Model and the multiplicative mixed model [PDF]

open access: yesFood Quality and Preference, 2019
Abstract A novel possibility for easy and open source based analysis of sensory profile data by a formal multiplicative mixed model (mumm) with fixed product effects and random assessor effects is presented by means of the generic statistical R-package mumm.
Pødenphant, Sofie   +3 more
openaire   +2 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Efficient Estimation of Marker Effects in Plant Breeding

open access: yesG3: Genes, Genomes, Genetics, 2019
The evaluation of prediction machines is an important step for a successful implementation of genomic-enabled selection in plant breeding. Computation time and predictive ability constitute key metrics to determine the methodology utilized for the ...
Alencar Xavier
doaj   +1 more source

Modelling tribimaximal neutrino mixing [PDF]

open access: yesPhysical Review D, 2009
We model tri-bimaximal lepton mixing from first principles in a way that avoids the problem of the vacuum alignment characteristic of such models. This is achieved by using a softly broken A4 symmetry realized with an isotriplet fermion, also triplet under A4. No scalar A4-triplet is introduced.
Hirsch, Martin   +2 more
openaire   +4 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

The Influence of Soil Deformability on the Seismic Response of 3D Mixed R/C–Steel Buildings

open access: yesInfrastructures
Following effective seismic codes, common buildings are considered to be made of the same material throughout the story distribution and based on an ideal rigid soil. However, in daily construction practice, there are often cases of buildings formed by a
Paraskevi K. Askouni
doaj   +1 more source

Spatial statistical analysis and selection of genotypes in plant breeding Seleção de genótipos e análise estatística espacial no melhoramento de plantas

open access: yesPesquisa Agropecuária Brasileira, 2005
The objective of this study was to evaluate the efficiency of spatial statistical analysis in the selection of genotypes in a plant breeding program and, particularly, to demonstrate the benefits of the approach when experimental observations are not ...
João Batista Duarte, Roland Vencovsky
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Avaliação genética de touros pelo modelo animal, modelo touro e método das companheiras de rebanho Sire evaluation by animal model, sire model and contemporary herdmate method

open access: yesRevista Brasileira de Zootecnia, 1999
As capacidades previstas de transmissão (PTA) para a produção de leite de 529 touros, usando o modelo animal (MA), modelo touro (MT) e o método das companheiras de rebanho (MCR), foram calculadas e comparadas por meio da correlação de ordem e valores, da
Rui da Silva Verneque   +4 more
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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