Results 91 to 100 of about 9,752,607 (260)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Diagnostics for generalised linear mixed models [PDF]
Generalized linear mixed models are generalized linear models that include random effects varying between clusters or 'higher-level' units of hierarchically structured data. Such models can be estimated using gllamm.
Sophia Rabe-Hesketh, Anders Skrondal
core
Quasi-Monte Carlo EM algorithm for MLEs in generalized linear mixed models
, 1998 Inferences for generalized linear mixed models are greatly hampered by the intractable integrated likelihood. In this paper numerical integration based on Quasi-Monte Carlo method is used to approximate the integral of the EM algorithm and then to fit ...
Robin Thompson +3 more
core +1 more source
Value for cultivation and use of upland rice cultivars tested in multienvironments
Crop Breeding and Applied Biotechnology, 2012 Data from 11 years of a breeding program for upland rice of the partner institutions Embrapa arroz e feijão, Epamig and UFLA conducted in 11 regions of Minas Gerais, were analyzed by the mixed model methodology.
Vanderley Borges +7 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Genetic divergence and parent selection of sugarcane clones
Crop Breeding and Applied Biotechnology, 2008 The objective of this study was to estimate the genetic divergence of 140 sugarcane clones of the series RB97, in phase T3 of the Sugarcane Genetic Improvement Program of the Universidade Federal do Paraná, at three locations by multivariate analysis ...
Valéria Rosa Lopes +5 more
doaj
Frontiers in Psychology, 2014 The association between socioeconomic status and child cognitive development, and the positive impact of interventions aimed at optimizing cognitive performance, are well documented.
María Soledad eSegretin +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Smooth-car mixed models for spatial count data [PDF]
Penalized splines (P-splines) and individual random effects are used for the analysis of spatial count data. P-splines are represented as mixed models to give a unified approach to the model estimation procedure.
Dae-Jin Lee, Maria Durban
core
Crop Breeding and Applied Biotechnology, 2008 The aim of this study was to compare REML/BLUP and Least Square procedures in the prediction and estimation of genetic parameters and breeding values in soybean progenies, F>.; and F 4.5 progenies were evaluated in the 2005/06 growing season and the Fy.4
Agnaldo Donizete Ferreira de Carvalho +2 more
doaj