Results 71 to 80 of about 1,513,668 (313)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Efficiency of indirect selection for green biomass production of Urochloa ruziziensis

open access: yesCrop Breeding and Applied Biotechnology, 2022
We aimed to measure the efficiency of visual selection of plant vigor for green biomass production of U. ruziziensis using single- and multitrait approaches to maximize the predictive accuracy of the genetic value.
Flavia Maria Avelar Gonçalves   +6 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mixed-effects regression models predicting media attention towards COVID-19.

open access: yes, 2022
Mixed-effects regression models predicting media attention towards COVID-19.
Reuben Ng (692015), Yi Wen Tan (7463702)
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Estimating nonparametric mixed logit models via EM algorithm [PDF]

open access: yes
The aim of this paper is to describe a Stata routine for the nonparametric estimation of mixed logit models using a Expectation-Maximisation algorithm. We also compare the performance of our estimator with respect to more typical parametric mixed logit ...
Daniele Pacifico
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Lack-of-fit tests in semiparametric mixed models. [PDF]

open access: yes
In this paper we obtain the asymptotic distribution of restricted likelihood ratio tests in mixed linear models with a fixed and finite number of random effects.
Claeskens, Gerda   +2 more
core  

Binary and Ordinal Random Effects Models Including Variable Selection [PDF]

open access: yes, 2010
A likelihood-based boosting approach for fitting binary and ordinal mixed models is presented. In contrast to common procedures it can be used in high-dimensional settings where a large number of potentially influential explanatory variables is available.
Groll, Andreas, Tutz, Gerhard
core   +1 more source

Using lexical variables to predict picture-naming errors in jargon aphasia

open access: yesFrontiers in Psychology, 2015
Introduction Individuals with jargon aphasia produce fluent output which often comprises high proportions of non-word errors (e.g., maf for dog). Research has been devoted to identifying the underlying mechanisms behind such output.
Catherine Godbold
doaj   +1 more source

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