Results 81 to 90 of about 9,752,607 (260)
The PX-EM algorithm for fast stable fitting of Henderson's mixed model
Genetics Selection Evolution, 2000 This paper presents procedures for implementing the PX-EM algorithm of Liu, Rubin and Wu to compute REML estimates of variance covariance components in Henderson's linear mixed models.
Van Dyk David A, Foulley Jean-Louis
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Be-Breeder: an R/Shiny application for phenotypic data analyses in plant breeding
Crop Breeding and Applied Biotechnology, 2018 In order to successfully achieve the final goal of genotype selection in plant breeding programs, many aspects must be considered and carefully thought regarding cost, time, and efficiency.
Filipe Inácio Matias +2 more
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Revista Brasileira de Fruticultura, 2009 O presente trabalho objetivou realizar a seleção genética de indivíduos híbridos superiores de coqueiro a partir da avaliação de 1.080 plantas para produção de frutos e de albúmen fresco, visando a ao fornecimento de sementes e/ou clones melhorados para ...
João Tomé Farias Neto +3 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Random-Effects Log-Linear Model with Poisson Distributions
Revstat Statistical Journal, 2003 In several applications data are grouped and there are within-group correlations. With continuous data, there are several available models that are often used; with counting data, the Poisson distribution is the natural choice. In this paper a mixed log-
Maria Alexandra Seco, António St. Aubyn
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Robust MM-Estimation and Inference in Mixed Linear Models [PDF]
Mixed linear models are used to analyse data in many settings. These models generally rely on the normality assumption and are often fitted by means of the maximum likelihood estimator (MLE) or the restricted maximum likelihood estimator (REML). However,
Stephane Heritier, Samuel Copt
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A variance shilf model for outlier detection and estimation in linear and linear mixed models [PDF]
, 2008 Includes abstract.Includes bibliographical references.Outliers are data observations that fall outside the usual conditional ranges of the response data.They are common in experimental research data, for example, due to transcription errors or faulty ...
Gumedze, Freedom Nkhululeko
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Adaptability and stability of maize varieties using mixed model methodology
Crop Breeding and Applied Biotechnology, 2012 The objective of this study was to evaluate the performance, adaptability and stability of corn cultivars simultaneously in unbalanced experiments, using the method of harmonic means of the relative performance of genetic values.
Flávia Ferreira Mendes +8 more
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